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Molecular Diagnostics

Image: The NEBNext Ultra II Directional RNA Library Prep Kit (Photo courtesy of New England Biolabs)

Biomarkers Predict Lyme Disease Post-Treatment Prognosis

Testing and diagnosis of the earliest stages of Lyme Disease (LD) have proven to be difficult or unreliable. The universally accepted diagnostic test for LD is a positive enzyme-linked immunosorbent assay (ELISA) followed by a positive western blot for immunoglobulin M (IgM) and IgG. More...
06 Dec 2022
Image: The Heatrich-BS assay can also help scientists study different subtypes of cancer for a low cost (Photo courtesy of NUS)

Low Cost, Highly Sensitive Blood Test for Cancer Makes Regular Monitoring Affordable

Scientists have discovered a novel low-cost method of testing for cancers. Called the Heatrich-BS assay, the new test sequences clinical samples that have been heated in order to isolate cancer-specific signatures found in a patient’s blood. More...
06 Dec 2022
Image: The Panall 8000 molecular diagnostic system will be launched in the first quarter of 2023 (Photo courtesy of Tianlong)

New All-In-One Molecular Diagnostic System Realizes True Sample In -Result Out Detection Process

Tianlong Science and Technology (Shaanxi, China) is all set to launch its new all-in-one molecular diagnostic system in the first quarter of 2023. More...
06 Dec 2022
Image: Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers (Photo courtesy of The Jackson Laboratory for Genomic Medicine)

Method Enables Targeted Profiling of Human Extrachromosomal DNA

Oncogene amplification is a key cancer-driving mechanism and frequently occurs on circular extrachromosomal DNA (ecDNA). ecDNA oncogene amplifications are present in half of human cancer types and up to one-third of tumor samples and are associated with poor patient outcomes. More...
05 Dec 2022
Image: Liquid biopsy approach delivers unparalleled sensitivity and specificity for detection of low-frequency mutant molecules (Photo courtesy of Pexels)

ctDNA-Based MRD Test to Detect As Few As One Mutant Molecule in a Million DNA Molecules

A best-in-class personalized cancer diagnostic test that is currently under development and planned for 2023 commercialization can detect as few as one mutant molecule in a million DNA molecules, positioning it as the most sensitive ctDNA-based MRD test for use in solid tumors. More...
02 Dec 2022
Image: A study has identified optimal blood tests for development of new therapies of Alzheimer’s disease (Photo courtesy of Pexels)

Study Identifies Optimal Blood Tests for Detection and Treatment of Early Stage Alzheimer’s

A new study has identified which blood tests are best at detecting Alzheimer’s disease during the earliest stages, and also another blood test that is optimal for detecting relevant treatment effects. These findings will speed up the development of new therapies that can slow down the disease progression. More...
02 Dec 2022
Image: A substance in the blood increases before diagnosis of pancreatic cancer (Photo courtesy of Pexels)

Blood Test for Protein Biomarker Could Detect Pancreatic Cancer at Very Early Stage

A new study has found that in some people diagnosed with pancreatic cancer, levels of a particular substance in their blood can be seen to start rising slowly as early as two years before the cancer was diagnosed. This raises the possibility for future research to find ways to detect the dreaded cancer earlier. More...
02 Dec 2022
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