Molecular Diagnostics

Genetic Mutation Causes Lethal Condition in Infants

Protein losing enteropathy is a condition of the gastrointestinal tract that results in loss of protein from the body, and often leads to severe abdominal swelling, malnutrition and early death in affected infants. More...
05 Aug 2015

$Image: Globoid cell leukodystrophy: Mulinucleated macrophages (\"globoid cells\") and loss of myelinated fibers in a case of Krabbe\'s leukodystrophy (Photo courtesy of Wikimedia Commons).$

Advanced Next-Generation Sequencing Assay Kit Now Available for the Diagnosis of Leukodystrophy

An advanced next-generation sequencing assay kit is now available to augment the use of MRI scans to diagnose the class of brain disorders known as leukodystrophies. More...
03 Aug 2015

Image: The high-throughput automated Panther system (Photo courtesy of Hologic Inc).

Genomic Assays Identify Chikungunya Virus in Blood Donors

The risk for transfusion-transmitted infection of Chikungunya virus is currently unclear, but several factors raise concern about possible transfusion-transmitted infection with this virus, including a 10% to 25% asymptomatic infection rate and high viremic titers in asymptomatic persons. More...
03 Aug 2015

Prenatal Testing May Also Detect Some Maternal Cancers

A new bioinformatics study shows that prenatal genetic test results, such as revealed by noninvasive prenatal testing (NIPT) for fetal chromosome abnormalities, may also detect underlying conditions in the mother, including cancer. More...
02 Aug 2015

Blood Test Could Identify Diabetes Decades Before It Develops

A small molecule circulates in the blood of people who are in the early stages of type 1 diabetes and a simple blood test could detect this biological marker years, maybe decades, before symptoms develop. More...
22 Jul 2015

Consensus Guidelines for Thyroid Cancer Molecular Tests Revised

National guidelines for thyroid cancer testing have been revised to reflect newly available tests that better incorporate personalized medicine into diagnosing the condition. More...
20 Jul 2015

$Image: Immunofluorescence image of human stomach section stained for ARHGAP26 (green), epithelial cadherin (red), and cell nuclei (blue). Epithelial cadherin is present in all epithelial cell types of the stomach, whereas ARHGAP26 is restricted to parietal cells (Photo courtesy of A*STAR\'s Genome Institute of Singapore).$