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Molecular Diagnostics

Image: Transmission electron micrograph (TEM) of the Varicella zoster virus (Photo courtesy of Dr. Erskine Palmer).

Multiplex Assays Detect HSV-1/2 And Varicella Zoster Virus

The performance of two multiplex real-time polymerase chain reactions to individual real-time PCR for the detection of herpes simplex virus-1, HSV-2, and Varicella zoster virus from clinical specimens have been compared.   More...
12 Jan 2015
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DNA Sequencing of Liquid Biopsy Specimens Increases Accuracy of Prostate Cancer Diagnosis

Next-generation sequencing analysis of DNA in the serum, a technique called liquid biopsy, can distinguish between prostate cancer patients, normal individuals, patients with benign hyperplasia, and those with noncancerous prostatitis.  More...
12 Jan 2015
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Newborn Screening Test Detects Severe Combined Immunodeficiency

Severe Combined Immunodeficiency is a group of disorders caused by defects in genes involved in the development and function of T-cells and other infection-fighting immune cells.   More...
07 Jan 2015
Image: Photomicrograph of ductal breast carcinoma in situ shows several ducts to be filled with carcinoma cells (Photo courtesy of Breastpath).

Breast Cancer Test Optimizes Treatment Recommendations

The first prospective outcomes data from a large Women's Healthcare Study Group for contemporary adjuvant breast cancer trials has identified patients who would be more likely to benefit from chemotherapy treatment.   More...
06 Jan 2015

Genome Analysis Study to Aid Diagnosis of Rare Developmental Disorders

First results from a study that will eventually incorporate complete genome analysis of 12,000 families in the United Kingdom and the Republic of Ireland have revealed 12 novel genes associated with rare and difficult to diagnose developmental disorders.  More...
06 Jan 2015
Image: Micrograph of an intrahepatic cholangiocarcinoma (right of image) adjacent to benign hepatocytes (left of image) (Photo courtesy of Wikimedia Commons).

Canadian Researchers Identify Mutations Linked to Rare Form of Liver Cancer

Canadian cancer researchers working with patients in China have identified mutations linked to the development of intrahepatic cholangiocarcinoma, a rare, highly fatal form of liver cancer that disproportionately affects individuals of Asian origin.  More...
05 Jan 2015
Image: Scanning electron microscope (SEM) photograph of fibroblasts in gel cultured on microfluidic chip (Photo courtesy of the University of Michigan).

Cell Culture Technique Leads to Tailor-Made Cancer Treatments

A novel in situ capture and culture methodology has been developed for ex vivo expansion of circulating tumor cells using a three dimensional co-culture model, simulating a tumor microenvironment to support tumor development.  More...
04 Jan 2015
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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