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Molecular Diagnostics

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De Novo Mutation Causes Fanconi Anemia

Fanconi anemia is clinically typified by susceptibility to bone marrow failure, leukemia, different types of solid tumors, and a strongly reduced life expectancy of the affected persons.    More...
10 Jan 2016
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Alzheimer's Risk Genes Linked to Brain Atrophy

Two genetic variants previously linked to Alzheimer's disease have been more specifically tied to brain atrophy that is characteristic of the disease.    More...
10 Jan 2016
Image: Colored Transmission electron micrograph of Clostridium difficile forming an endospore (red) (Photo courtesy of Dr. J. Thomas Lamont).

New Infectious Disease Test Promises Quick Diagnosis

Early detection of specific pathogens has long been recognized as a vital strategy in the control of infectious diseases because it can lead to timely care of patients and prevent potential outbreaks.   More...
05 Jan 2016
Image: Applied Biosystems ABI 373 XLDNA sequencer (Photo courtesy of Perkin-Elmer).

Nosocomial Environmental Contamination by MERS-CoV Investigated

Although Middle East Respiratory Syndrome coronavirus is characterized by a risk of nosocomial transmission, the detailed mode of transmission and period of virus shedding from infected patients are poorly understood.   More...
04 Jan 2016
Image: A screenshot from the Mykrobe Predictor software package shows results for an analysis of a methicillin-resistant Staphylococcus aureus (MRSA) bacterium (Photo courtesy of Mykrobe [University of Oxford]).

Computer Program Predicts Drug Resistance by Evaluating Whole Genome Sequencing Data

A software package is being evaluated in the United Kingdom that can identify a bacterium from the DNA sequence of its genome and predict which antibiotics will kill it.  More...
03 Jan 2016

Low Zinc May Indicate Potential Breast-Feeding Problems

A new study provides an important step toward identifying breast-fed infants at risk for severe zinc deficiency. Identifying mothers with abnormally low levels of zinc in breast milk may enable to more quickly determine those more likely to have trouble breast-feeding.   More...
27 Dec 2015
Image: Immunohistochemistry of estrogen receptor (ER)-positive (brown), in metastatic breast cancer (Photo courtesy of Dr. Steven Halls).

Different Mutations May Predict Different Responses to Chemotherapy

Among patients with estrogen receptor-positive, metastatic breast cancer, those who had a D538G and/or a Y537S mutation in the estrogen receptor 1 gene, as detected in cell-free DNA obtained from patient blood samples, had significantly worse median overall survival.  More...
21 Dec 2015
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.