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Molecular Diagnostics

Image: Histopathology of a testicular seminoma with classical histologic features including a prominent lymphoid stromal infiltrate and typical cytomorphology (Photo courtesy of Mattopaedia).

Testicular Cancer Risk Comes from Inherited Genetic Faults

Testing for a range of genetic variants linked to testicular cancer could be effective in picking out patients who are at substantially increased risk, and therefore, potentially opening up ways of preventing the disease.  More...
20 Sep 2015
Image: Histopathology of advanced gastric carcinoma of the intestinal type shows gland-forming adenocarcinoma and adjacent intestinal metaplasia (Photo courtesy of Drs. Shabnam Bashir and Sudip Raina).

Biomarker Helps Predict Stomach Cancer Survival

A biomarker has been identified in patients with stomach cancer that starves tumors of their blood supply and reduces the ability of cancer cells to spread to other parts of the body.   More...
16 Sep 2015
Image: Histopathology of hilar cholangiocarcinoma or Klatskin tumor (Photo courtesy of the Nephron).

Independent Prognostic Biomarker Found for Klatskin Tumor Patients

Curative treatment of intrahepatic cholangiocarcinoma and hilar cholangiocarcinoma is limited to surgical resection or orthotopic liver transplantation, however, not all patients benefit from a surgical approach and suffer from early tumor recurrence.  More...
16 Sep 2015
Image: The \"Japonica Array\" contains 659,253 SNPs, including tag SNPs for imputation, SNPs of Y chromosome and mitochondria, and SNPs related to previously reported genome-wide association studies and pharmacogenomics (Photo courtesy of Tohoku Medical Megabank Organization).

Custom-Designed SNP Array Facilitates Japanese Genomic Studies

Japanese genomic researchers have created a single nucleotide polymorphism array optimized for studies on the Japanese population.  More...
16 Sep 2015
Image: Bone marrow aspirate smear showing blasts with high nuclear: cytoplasmic ratio from a patient with acute myeloid leukemia (Photo courtesy of the Cleveland Clinic).

Relapse In Leukemia Linked to Genetic Mutations

For patients with an often-deadly form of leukemia, lingering cancer-related mutations detected after initial treatment with chemotherapy, are associated with an increased risk of relapse and poor survival.  More...
14 Sep 2015
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Blood Test Developed to Catch Pancreatic Cancer Early

Pancreatic cancer is the fourth most common cause of cancer-related death in the USA and has a five-year survival rate of only 6%, which is the lowest rate of all types of cancer and this low survival rate is partially attributed to the difficulty in detecting pancreatic cancer at an early stage.   More...
08 Sep 2015

Liquid Biopsy Assay Predicts Risk of Breast Cancer Relapse

A liquid biopsy method for tracking mutations in circulating breast cancer cells enables physicians to predict cancer recurrence as early as eight months before physical symptoms appear.   More...
06 Sep 2015
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.