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Molecular Diagnostics

Image: Eprobe, a highly efficient and reliable fluorescent probe for PCR DNA amplification techniques and DNA analysis in hybridization experiments, has been developed by researchers from the Japanese firms RIKEN and K.K. DNAFORM. This technology will enable the development of new, advanced assays for DNA-based genetic testing and help to bring the benefits of genome-wide sequencing studies to patients in the clinic (Photo courtesy of RIKEN).

New Dual-Functional Fluorescent Probe for DNA Hybridization and Melting Point Analysis

Japanese researchers have described a new approach for combining real-time PCR amplification and melting curve analysis in a single-tube reaction, which provides a powerful means for new mutation detection assays. More...
20 Aug 2013
Image: Scanning electron micrograph of Giardia lamblia (Photo courtesy of Dr. Stan Erlandsen).

Novel Molecular Assay Diagnoses Eight Gastrointestinal Parasites

A novel, rapid, high-throughput quantitative multiparallel real-time polymerase chain reaction platform has been developed for the diagnosis of gastrointestinal parasites. More...
19 Aug 2013
Image: Alzheimer’s disease: senile plaques in cerebral cortex (Photo courtesy of Wikimedia Commons).

Accurate Blood Test Discriminates Alzheimer's Disease

A pioneering blood test has been identified that may provide a much earlier diagnosis of Alzheimer's disease and other degenerative disorders. More...
13 Aug 2013
Image: Mycobacterium tuberculosis (Photo courtesy of the University of Wisconsin).

Low Expression of Immune Response Gene Increases TB Risk

A genetic mutation in Africans with human immunodeficiency virus has been identified that puts them at a much higher risk for tuberculosis infections. More...
12 Aug 2013
Image: SLAN real-time polymerase chain reaction instrument (Photo courtesy of Daan Diagnostics Ltd).

Multitarget Assay Improves MRSA Screening

A molecular screening assay that targets three genes of methicillin-resistant Staphylococcus aureus is suggested as more accurate than commercial assays that target a single gene. More...
12 Aug 2013
Image: Microarray assay result (Photo courtesy of Ashley Vance).

Gene Expression Profiles Define Microbial Infection

A molecular test distinguishes between viral and bacterial infections in children with fever by profiling the activity of genes in a blood sample. More...
08 Aug 2013
Image: An encapsulated thymoma (Photo courtesy of the [US] Armed Forces Institute of Pathology.

Gene Signature Determines Metastatic Behavior in Thymomas

A molecular test may be able help patients diagnosed with thymoma avoid certain cancer treatments associated with severe adverse events. More...
06 Aug 2013
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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