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Molecular Diagnostics

Image: Dark field scattering micrograph showing the accumulation of amyloid structures (Photo courtesy of the University of Toronto).

Molecular Basis of Alzheimer’s Disease Determined

Alzheimer's disease is thought to be caused by the buildup of abnormal, thread-like protein deposits in the brain, known as beta-amyloid fibrils. More...
02 Oct 2013
Image: Immunofluorescence cell staining using FGFR1 antibody (Photo courtesy of Abcam).

Molecular Test Identifies Indolent Prostate Cancer

The level of expression of three genes associated with aging can be used to predict whether seemingly low-risk prostate cancer will remain slow growing. More...
30 Sep 2013
Image: Blood smear of precursor B-cell acute lymphoblastic leukemia (Photo courtesy of Peter Maslak).

Genetic Cause of Childhood Leukemia Identified

A genetic link to the risk of childhood acute lymphoblastic leukemia has been identified and testing for this mutation may allow affected families to prevent leukemia in future generations. More...
26 Sep 2013
Image: Chromosomes imaged with Fluorescence in situ hybridization (FISH) showing a pair of yellow dots as areas of genes are missing due to deleted genes on chromosome 22 (Photo courtesy of Stanford University).

Genetic Deletion Linked to Early-Onset Parkinson's Disease

A neoteric link has been discovered between early-onset Parkinson's disease and a microdeletion of a piece of DNA from chromosome 22. More...
25 Sep 2013
Image: Polymerase chain reaction Mastercycler gradient (Photo courtesy of Eppendorf).

Molecular Method Detects Colon Cancer Earlier

Techniques that identify gene variations that have been linked to colon cancer, may soon allow doctors to diagnose the disease in the very first stages, potentially saving patients' lives. More...
24 Sep 2013
Image: ABI Prism 7700 Sequence Detection System (Photo courtesy of Applied Biosystems).

Methods Evaluated for HER2 Status in Breast Cancer

The human epidermal growth factor receptor 2 gene is overexpressed or amplified in approximately 15% to 20% of all breast cancers leading to a poorer prognosis. More...
23 Sep 2013
Image: Histology of mitochondrial encephalomyopathy with ragged red fibers (Photo courtesy of Dr. K.K. Abu-Amero).

Gene Mutation Causes Devastating Mitochondrial Diseases

A novel disease gene has been identified in which mutations cause rare but devastating genetic diseases known as mitochondrial disorder. More...
19 Sep 2013
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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