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Molecular Diagnostics

MicroRNAs Predict Likelihood of Breast Cancer Metastasis

The discovery that breast cancer patients who experienced quick relapses tended to have low levels of the microRNA miR-21 and high levels of the microRNA miR-205 in their tumor tissues suggests that measurement of these two biomarkers could identify women at risk of metastasis.  More...
22 Jan 2014
Image: The Nanodrop 1000 Spectrophotometer (Photo courtesy of Thermo Fisher Scientific).

Blood Test Locates Gene Defects Linked to Cancer

A simple blood test could be developed to determine whether gene mutations associated with pancreatic cancer exist without the need of locating and testing tumor tissue.  More...
21 Jan 2014

Horizon and AstraZeneca Announce Oncology Agreement

Horizon Discovery and AstraZeneca have entered into research collaboration and license agreement to explore a range of oncology-relevant genotypes with the aim of identifying and validating a number of novel drug targets.  More...
21 Jan 2014
Image: TaqMan Reverse Transcription Kit for microRNA (Photo courtesy of Life technologies).

Blood-Based Biomarkers Validated for Mild Cognitive Impairment

A minimally invasive test is essential for the early detection and monitoring of Alzheimer's and other neurodegenerative diseases for both drug development and planning of patient care.  More...
20 Jan 2014

Determination of Circulating CPN Cleavage Peptides Enables Early Diagnosis of Breast Cancer

The concentration of circulating peptides produced by CPN cleavage reflects the CPN activity in tumors, and analysis of these biomarkers demonstrates potential for the noninvasive and early diagnosis of breast cancer.  More...
20 Jan 2014
Image: MammaPrint, a prognostic 70-gene profile for early-stage breast cancer (Photo courtesy of Agendia).

Molecular Diagnostics Optimized for Breast Cancer Tissue Samples

A prognostic 70-gene profile assay for early-stage breast cancer has been available for fresh tissue, and improvements in ribonucleic acid processing have enabled microarray diagnostics for formalin-fixed, paraffin-embedded tissue.  More...
16 Jan 2014
Image: The Illumina Genome analyzer (Photo courtesy of Illumina).

Cervical Cancer Genomic Study Completed

A comprehensive genomic analysis of cervical cancer in two patient populations has been completed and recurrent genetic mutations have been identified not previously found in cervical cancer.  More...
14 Jan 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.