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Molecular Diagnostics

Image: The PyroMark Q96 ID instrument for quantitative analysis of genetic or epigenetic DNA modifications using Pyrosequencing technology (Photo courtesy of Qiagen).

Biomarkers Could Lead to Early Diagnosis of Colorectal Cancer

An understanding of early genetic and epigenetic changes in colorectal cancer would aid in diagnosis and prognosis for patients suffering from this disease.   More...
14 Nov 2013
Image: Luminex MultiAnalyte System (Photo courtesy of Luminex).

Immunodeficiency Disorder CVID Caused by Gene Mutation

Common variable immunodeficiency is a heterogeneous disorder characterized by antibody deficiency, poor humoral response to antigens, and recurrent infections.   More...
07 Nov 2013
Image: Immunohistochemistry of paraffin-embedded human ovary tumor using P53 antibody (Photo courtesy of Proteintech).

Genetic Errors Identified in 12 Major Cancer Types

The latest sequencing and analysis methods have been used to identify somatic variants across thousands of tumors, and 127 significantly mutated genes were detected.   More...
07 Nov 2013
Image: Histopathology of melanoma (Photo courtesy of Priscilla Lynch).

Biomarker Helps Guide Treatment of Melanoma

A functional biomarker can predict whether mutant melanomas respond to drugs targeting a particular gene and could help guide the treatment of patients with these cancers.  More...
06 Nov 2013

Analytic Validation of Cancer Genomic Profiling Assay Demonstrated

A 24-month, multi-institution collaboration demonstrated the analytic validation of a cancer genomic profiling assay.  More...
06 Nov 2013
Image: Bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia (Photo courtesy of VashiDonsk).

Inherited Gene Variation Linked to Relapsing Pediatric Leukemia

An inherited gene variation has been linked to a nearly four-fold increased risk of developing a pediatric acute lymphoblastic leukemia subtype that is associated with a poor prognosis.  More...
05 Nov 2013
Image: Confocal microscopy of a cell with lysosomes (green) with accumulated amyloid-beta (red) (Photo courtesy of Linköping University).

Potential Biomarkers Found for Early Alzheimer's Diagnosis

The presymptomatic stage of Alzheimer’s disease occurs at least one decade before the clinical onset, highlighting the need for validated biomarkers that reflect this early period.  More...
05 Nov 2013
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.