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Molecular Diagnostics

Image: Micro Ribonucleic Acid Analysis Kits (Photo courtesy of Exiqon).

Potential Molecular Biomarker Identified for Sepsis

A biomarker or biological footprint for sepsis that could form the basis of a rapid bedside blood test that returns results within two hours has been revealed.   More...
28 Oct 2013
Image: Light photomicrograph of brain tissue reveals the presence of typical amyloid plaques found in a case of variant Creutzfeldt-Jakob disease (vCJD). Magnified 158x, and stained by the H&E (hematoxylin and eosin) staining technique (Photo courtesy of the US Centers for Disease Control (CDC)).

New Survey Reveals Large Number of Prion Carriers in the United Kingdom

 A second immunohistochemistry survey of archived appendix samples conducted in the United Kingdom has found that the number of individuals carrying variant Creutzfeldt-Jakob disease prions was more than double that found in the first survey. More...
28 Oct 2013
Image: Histopathology of colonic carcinoid stained by hematoxylin and eosin (Photo courtesy of Wikipedia).

Hereditary Cancer Assay Improves Colon Cancer Testing

 Patients with a family history of colon cancer also are vulnerable to other cancers including breast, ovarian, endometrial and stomach cancer.  More...
23 Oct 2013
Image: Micrograph of papillary thyroid carcinoma tall cell variant (Photo courtesy of Nephron).

Protein Identified That May Predict Thyroid Cancer Recurrence

A protein called Programmed Death Ligand 1, can help to predict which thyroid cancer patients will most likely have a recurrence of the disease. More...
23 Oct 2013
Image: Photomicrograph of a salivary gland with sites of inflammation indicative of Sjögren's syndrome (Photo courtesy of US National Institute of Dental and Craniofacial Research).

Six Additional Sjögren's Syndrome Genes Identified

 The first genome-wide association study for Sjögren's syndrome has been completed and six new disease-related genes have been identified. More...
23 Oct 2013
Image: RTD 1000 picodroplet-based Polymerase chain reaction-setup system (Photo courtesy of RainDance Technologies).

Diagnostic Test Clinically Validated for Breast Cancer Mutations

An innovative technique using second-generation sequencing technology is as sensitive as the standard methodology but has the potential to improve the efficiency and productivity of genetic testing laboratories. More...
22 Oct 2013
Image: Barrett's esophagus (left part of image). The characteristic goblet cells are stained blue. Normal stratified squamous epithelium is seen on the right of the image (Photo courtesy of Wikimedia Commons).

Genome-Wide Association Study Identifies New Susceptibility Loci for Esophageal Adenocarcinoma and Barrett's Esophagus

Results obtained during a large genome-wide association study yielded three previously unknown gene associations linked to the risk of esophageal cancer and its precursor, Barrett's esophagus. More...
21 Oct 2013
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