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Molecular Diagnostics

Image: The NutriPhone is a mobile diagnostics platform for monitoring individual vitamin and micronutrient levels was adapted to work with a rapid point-of-care assay system (Photo courtesy of Cornell University).

Rapid POC Assay Detects Micronutrient Deficiencies

A technology that could transform the way nutritional deficiency testing is done worldwide is based on a novel 15-minute point-of-care assay system that enables determination of vitamin A, iron, and inflammation status. More...
18 Dec 2017
Image: Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized (Photo courtesy of Wikimedia Commons).

Detection of Circulating DNA Predicts Poor Prognosis

Analysis of circulating tumor DNA for mutations in the BRAF and NRAS genes was found to accurately predict the likely recurrence of malignant melanoma. More...
18 Dec 2017
Image: The Mastercycler Nexus thermal cycler (Photo courtesy of Eppendorf).

Multiplexed Amplification Evaluated for Viral Hemorrhagic Fever Diagnostics

Viral hemorrhagic fever is a severe and potentially lethal disease, characterized by fever, malaise, vomiting, mucosal and gastrointestinal bleeding, and hypotension, in which multiple organ systems are affected. More...
14 Dec 2017
Image: The ScanScope systems (Photo courtesy of Leica/Aperio).

Five New Genes Identified for ALS

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is characterized by loss of motor neurons in the brain, brainstem and spinal cord, with concurrent muscle atrophy and is typically fatal within 2–5 years from diagnosis. More...
13 Dec 2017
Image: A diagram of the human prostate gland, roughly the size and shape of a walnut, bisected by the urethra. The locations of each of an individual\'s 13 biopsy cores are indicated. Information obtained via single-cell sequencing from cells sampled from each core indicates the likely location of a cancerous tumor (dotted lines encompassing cores 2, 3 and 6) (Photo courtesy of Cold Spring Harbor Laboratory).

Single Cell Genomics Utilized for Evaluation of Prostate Cancer

A distinction between indolent and aggressive disease is a major challenge in diagnostics of prostate cancer. Histopathology of tissue biopsies is a standard method used for evaluating cancer risk. Many decades of experience have led to classification of the histological types correlated with clinical outcome. More...
13 Dec 2017
Image: A diagram of the Kompetitive Allele Specific Polymerase Chain Reaction (PCR KASP) method (Photo courtesy of J.P. Livingstone).

Genetic Link Found Between Immune System and Lymphoma

Classical Hodgkin lymphoma (cHL) is a lymphoid malignancy of germinal center (GC) B-cell origin, which is characterized by Hodgkin and Reed–Sternberg (HRS) cells with a dominant background population of reactive inflammatory cells. More...
12 Dec 2017
Image: A stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia (Photo courtesy of VashiDonsk).

Missing DNA Fragments Could Predict Leukemia Relapse

A new risk scoring system has been developed for children with leukemia based on missing DNA fragments or 'microdeletions'. The risk score will allow doctors to better predict the chance of relapse of a subgroup of children currently hidden in a lower risk group. More...
11 Dec 2017
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AltoStar HIV RT-PCR Kit 1.5


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.