Molecular Diagnostics
Gene Sequencing Reveals Mutations in Endometriosis
Endometriosis occurs when tissue lining the uterus forms and grows outside of the organ, most often into the abdomen. The disease occurs in up to 10% of women before menopause and half of those with abdominal pain and infertility problems. More...24 May 2017
Molecular Test Predicts Blood Cancer Patient Survival
Technology that can detect the length of small DNA structures in cancer cells could hold the key to predicting the outcome of patients with two different types of blood cancer. The test, used in conjunction with current methods, may help doctors make better choices about the most appropriate and effective treatment option for individual patients. More...24 May 2017
Elevated Levels of Beta-2 Microglobulin Linked to Increased Stroke Risk
Beta-2 microglobulin, also known as B2M, is a component of the MHC class I molecules, which are present on all nucleated cells. They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of non-self-proteins from within the cell to cytotoxic T-cells; this will trigger an immediate response from the immune system against a particular non-self-antigen displayed with the help of an MHC class I protein. More...22 May 2017
Test Predicts Benefit of Targeted Cancer Treatments
There is an urgent need to develop biomarker strategies to a priori identify castration-resistant prostate cancer (CRPC) patients who will derive minimal benefit from androgen receptor (AR) targeting and offer them an alternative treatment paradigm. More...17 May 2017
Genomic Duplication Responsible for Rare Skin Disease
Through data analysis, ancestry mapping, genomic comparison, and international collaboration, researchers have identified the genetic mutation that causes the rare skin disease keratolytic winter erythema (KWE), or “Oudtshoorn skin,” in South African and Norwegian families. More...15 May 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.