Molecular Diagnostics
Elevated Levels of Beta-2 Microglobulin Linked to Increased Stroke Risk
Beta-2 microglobulin, also known as B2M, is a component of the MHC class I molecules, which are present on all nucleated cells. They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of non-self-proteins from within the cell to cytotoxic T-cells; this will trigger an immediate response from the immune system against a particular non-self-antigen displayed with the help of an MHC class I protein. More...22 May 2017
Test Predicts Benefit of Targeted Cancer Treatments
There is an urgent need to develop biomarker strategies to a priori identify castration-resistant prostate cancer (CRPC) patients who will derive minimal benefit from androgen receptor (AR) targeting and offer them an alternative treatment paradigm. More...17 May 2017
Genomic Duplication Responsible for Rare Skin Disease
Through data analysis, ancestry mapping, genomic comparison, and international collaboration, researchers have identified the genetic mutation that causes the rare skin disease keratolytic winter erythema (KWE), or “Oudtshoorn skin,” in South African and Norwegian families. More...15 May 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.