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Molecular Diagnostics

Image: Researchers reanalyzed raw bacterial DNA sequence data from several studies and confirmed previously reported types of bacteria associated with colorectal cancer and identified other bacteria not previously associated with the disease (Photo courtesy of Baylor College of Medicine).

Panel of Gut Bacteria Diagnostic for Colorectal Cancer

Reanalysis and standardization of data from several published studies has enabled a team of molecular microbiologists to identify a panel of gut microflora that is more prevalent in the stools of patients with colorectal cancer than it is in the stools of normal individuals. More...
01 May 2017
Image: The illumigene Malaria is a diagnostic test for malaria that uses Loop-Mediated Isothermal Amplification (LAMP) technology to amplify DNA and detect the presence of the malaria parasite (Photo courtesy of Meridian Bioscience).

LAMP-based Assay Launched for Detection of Malaria

A new molecular diagnostic kit for the detection of the malaria parasite has been described as being up to 80,000 times more sensitive at detecting the malaria parasite than current testing options. More...
01 May 2017
Image: A new blood-based assay enables rapid identification of specific genetic mutations in patients with non-small-cell lung cancer (NSCLC), which helps clinicians select the best treatment option (Photo courtesy of Biodesix).

Rapid Assay Identifies Genetic Mutations Associated with NSCLC

A rapid blood-based diagnostic assay is now available to identify genetic mutations associated with non-small-cell lung cancer (NSCLC), which is the first step in establishing personalized treatment for the patient. More...
01 May 2017
Image: The LSM 700 laser scanning microscope (Photo courtesy of Zeiss).

Biomarker Identified for Aggressive Early Stage Cancer

Breast cancer begins as anomalous cells that divide out of control, usually in the milk ducts and in almost all cases, a patient does not succumb to the initial cancer but to the secondary tumors after the cancer has spread. More...
27 Apr 2017
Image: The Ziplex System, a medium-density microarray platform (Photo courtesy of Axela).

Blood Test Could Detect Abusive Head Trauma in Infants

A blood test has been developed and refined that could help clinicians identify infants who may have had bleeding of the brain as a result of abusive head trauma, sometimes referred to as shaken baby syndrome. More...
26 Apr 2017
Image: The fluorescent signal demonstrated by the Specific High Sensitivity Enzymatic Reporter UnLOCKing (SHERLOCK) system using CRISPR-Cas (Photo courtesy of the Broad Institute).

Sensitive NA Detection Aids Pathogen Diagnoses

Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring, and can be used to diagnose infections, such as Zika and dengue, with a high level of sensitivity. More...
26 Apr 2017
Image: A diagram of the method developed to detect and map DNA methylation, which can be a sign of cancer, by threading the DNA through a tiny hole in a thin sheet of conductive material with a current running through it (Photo courtesy of Aditya Sarathy, University of Illinois).

Detecting Cancer as DNA Changes Could Enhance Diagnosis

DNA methylation is an epigenetic modification involving the addition of a methyl group to DNA, which is heavily involved in gene expression and regulation, thereby critical to the progression of diseases such as cancer. More...
26 Apr 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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