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Molecular Diagnostics

Image: A scanning electron micrograph (SEM) of an ovarian cancer cell (Photo courtesy of Steve Gschmeissner / SPL).

MicroRNA-based Assay Proposed for Early Detection of Cancer

Cancer researchers have proposed using a network of circulating microRNAs to diagnose ovarian carcinoma at a stage earlier than currently possible. More...
13 Nov 2017
Image: The Solana RSV + hMPV Assay is a rapid qualitative in vitro diagnostic test for the detection and differentiation of Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) viral RNA (Photo courtesy of Quidel).

RSV Plus Human Metapneumovirus Assay Approved

Viral infections are the most frequent causes of morbidity and mortality due to respiratory dysfunction worldwide, especially in children under five years of age. Several studies have reported the association of Human Metapneumovirus (hMPV) and Respiratory Syncytial Virus (RSV) with acute respiratory infection. More...
09 Nov 2017
Image: A Schistosoma japonicum egg in feces (unstained, high power). The eggs of this fluke are smaller than those of S. mansoni and S. haematobium. They are ovoid and have a thin, clear shell and a spine or hook-like structure that may be inconspicuous (Photo courtesy of Florida Gulf Coast University).

Droplet Digital PCR Detects Schistosomiasis DNA in Samples

Schistosoma japonicum is the only human blood fluke that occurs in China and Philippines and also in Sri Lanka. It is the cause of schistosomiasis japonica, a disease that still remains a significant health problem especially in lake and marshland regions. More...
08 Nov 2017
Image: The Applied Biosystems 7500 Real-Time PCR systems offer high performance, multicolor real-time polymerase chain reactions (Photo courtesy of Thermo Fisher Scientific).

Molecular Assay Rapidly Detects Hemorrhagic Fever Virus

Crimean-Congo Hemorrhagic fever Virus (CCHFV) is a rapidly emerging vector-borne pathogen and the cause of a virulent hemorrhagic fever affecting large parts of Europe, Africa, the Middle East and Asia. More...
08 Nov 2017
Image: A photomicrograph of a demyelinating multiple sclerosis lesion. Immunohistochemical CD68-staining highlights numerous macrophages (brown); original magnification 10x (Photo courtesy of Wikimedia).

Study Pinpoints Biomarker Signature of MS

Researchers have identified unique dysregulated microRNAs (miRNAs) from exosomes in the blood of Multiple Sclerosis (MS) patients. The findings could lead to development of a simple diagnostic blood test for this debilitating chronic neurologic disease. More...
07 Nov 2017

Genetics Helps Determine Warfarin Dose for Joint Surgery

A five-year study – the Genetics Informatics Trial of Warfarin to Prevent Deep Venous Thrombosis (GIFT) – finds that genetic testing can help determine the safest dose of the blood thinner warfarin, with fewer side effects, for patients undergoing joint replacement surgery. More...
06 Nov 2017
Image: An illustration of individual breast cancer tumors (Tumors A–D) with cells in varying differentiation states (shown in different colors) within a tumor (Image courtesy of Yeo SK and Guan J-L / Trends in Cancer).

Single-Cell Diagnostics Advocated for Breast Cancer Subtyping

In an opinion article based their analysis of studies, two medical researchers argue that women diagnosed with breast cancer (BC) would likely benefit from treatment based also on identifying the molecular subtype of different cells within their tumors, in addition to current molecular and histopathology testing of collections of tumor cells. More...
06 Nov 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.