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Clinical Chemistry

Image: Synergy HT Multi-Mode microplate reader (Photo courtesy of Biotek).

Assay Detects Urinary Proteins in Bladder Cancer

A high-throughput assay has been developed for the detection of tyrosine-phosphorylated proteins in urine of bladder cancer patients. More...
08 Jul 2013

Immunohistochemistry as Effective as DNA Hybridization for Detecting ALK Rearrangement in Lung Cancer Patients

Researchers demonstrated that immunohistochemistry provided a reliable and cost-effective diagnostic approach in routine pathologic laboratories for the identification of patients with non-small-cell lung cancer. More...
08 Jul 2013
Image: Human pancreas stained with anti-glutamic acid decarboxylase 65 antibody (Photo courtesy of Mybiosource).

Blood Test Predicts Diabetes Mellitus Type 1 Risk

Type 1 diabetes usually has a preclinical phase identified by circulating islet autoantibodies, but the rate of progression to diabetes after seroconversion to islet autoantibodies is equivocal. More...
04 Jul 2013
Image: Genomic structure of HPV (Photo courtesy of the [US] National Institutes of Health).

Antibody Against HPV Protein a Potential Biomarker for Oropharynx Cancer

Antibodies against the human papillomavirus E6 protein were identified in the blood of individuals who developed oropharynx cancer as long as 10 years before onset of the disease. More...
04 Jul 2013
Image: Heinz bodies in erythrocytes indicative of G6PD-deficiency (Photo courtesy of Institute of Tropical Medicine).

Enzymatic Assay Validated for G6PD Deficiency

The distribution of the most common human enzyme defect, glucose-6-phosphate dehydrogenase deficiency, is linked to areas of high malaria endemicity. More...
02 Jul 2013
Image: Acetone detection by nanotube-titanium dioxide hybrids (Photo courtesy of University of Pittsburgh.

Sensor Technology Detects Diabetes by Breath Analysis

A sensor technology could significantly simplify the diagnosis and monitoring of diabetes through breath analysis alone. More...
02 Jul 2013
Image: Fluorescent protein in Unagi muscle cells (Photo courtesy of RIKEN).

Eel Fluorescent Protein Revolutionizes Bilirubin Assay

A fluorescent protein from freshwater eels could serve as the basis for a revolutionary new clinical test for bilirubin, a critical indicator of human liver function, hemolysis, and jaundice. More...
01 Jul 2013
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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