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Clinical Chemistry

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Noninvasive Test Identifies Childhood Metabolic Disease Risk

Salivary biomarkers have been used as a tool for identifying children who are at risk for developing Type 2 diabetes.  More...
25 Jun 2014
Image: A photomicrograph of a paraganglioma, a carotid body tumor (Photo courtesy of Nephron).

Rare Adrenal Tumors Diagnoses Require Blood and Urine Testing

Clinical Practice Guideline for the diagnosis and treatment of two types of rare adrenal tumors, pheochromocytomas and paragangliomas, has been issued.  More...
24 Jun 2014
Image: A linear ion trap combined with a Fourier transform ion cyclotron resonance (LTQ-FT) mass spectrometer (Photo courtesy of Thermo Scientific).

Humans May Benefit from Canine Bladder Cancer Assay

A unique group of proteins have been identified that indicate the presence of transitional cell carcinoma, the most common cause of bladder cancer and may lead to a new assay which could better diagnose this disease in both dogs and humans.   More...
23 Jun 2014
Image: The BrukerAutoflex MALDI-TOF mass spectrometer (Photo courtesy of Bruker-Daltonics).

Cutaneous Leishmaniasis Species Identified by Mass Spectrometry

Cutaneous leishmaniasis is caused by several Leishmania species that are associated with variable outcomes before and after therapy and optimal treatment decision is based on an accurate identification of the infecting species.  More...
18 Jun 2014
Image: The schematic shows glucose molecules sliding along the biochip sensor surface illuminated by different colors. Change in light intensity transmitted through the slits of each plasmonic interferometer can be used to measure the glucose concentration in saliva (Photo courtesy of Domenico Pacifici, PhD).

Salivary Glucose Levels Measured by Biochip Sensor

A new biochip sensor has been developed that can selectively measure concentrations of glucose in a complex solution similar to human saliva.  More...
18 Jun 2014
Image: Histopathology of chronic obstructive pulmonary disease (COPD) showing hyperplasia of mucous glands and infiltration of the airway wall with inflammatory cells (Photo courtesy of Dr. Paul Kleinschmidt MD).

Breath Test Distinguishes Lung Cancer from Other Pulmonary Diseases

A test of organic compounds in exhaled breath can distinguish patients with lung cancer from patients with chronic obstructive pulmonary disease, and can also define the stage of any cancer present.  More...
11 Jun 2014
Image: Sarah Kee, Quality Control Scientific Consultant at Randox, has given a series of talks about the often overlooked importance of accurate calibration in providing reliable test results for patients (Photo courtesy of Randox).

Calibration First Vital Step to Reliable Lab Results

A quality control consultant has reemphasized the obvious but still often overlooked importance of performing high-quality calibrations to provide physicians and patients with accurate laboratory results.   More...
04 Jun 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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