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Clinical Chemistry

A Discrete Gene Signature Is a Diagnostic and Predictive Biomarker for Kidney Transplant Rejection

A genetic signature comprising two messenger RNA molecules that encode immune system proteins and one noncoding RNA molecule that participates in protein production has been shown to be diagnostic and prognostic of acute cellular rejection in kidney transplants. More...
15 Jul 2013

Three Automated Assays for Cancer Diagnosis and Monitoring Launched

Three automated assays, which will provide clinicians with information to aid the diagnosis and monitoring of thyroid and lung cancer patients, have been added to an assay menu. More...
15 Jul 2013
Image: Histology of severe coronary atherosclerosis (Photo courtesy of Medical Educational).

DNA Blood Test Identifies Serious Heart Problems

DNA fragments in the blood may help physicians quickly learn if chest pain means that the patient has narrowed heart arteries, which lead to coronary heart disease. More...
09 Jul 2013
Image: Synergy HT Multi-Mode microplate reader (Photo courtesy of Biotek).

Assay Detects Urinary Proteins in Bladder Cancer

A high-throughput assay has been developed for the detection of tyrosine-phosphorylated proteins in urine of bladder cancer patients. More...
08 Jul 2013

Immunohistochemistry as Effective as DNA Hybridization for Detecting ALK Rearrangement in Lung Cancer Patients

Researchers demonstrated that immunohistochemistry provided a reliable and cost-effective diagnostic approach in routine pathologic laboratories for the identification of patients with non-small-cell lung cancer. More...
08 Jul 2013
Image: Human pancreas stained with anti-glutamic acid decarboxylase 65 antibody (Photo courtesy of Mybiosource).

Blood Test Predicts Diabetes Mellitus Type 1 Risk

Type 1 diabetes usually has a preclinical phase identified by circulating islet autoantibodies, but the rate of progression to diabetes after seroconversion to islet autoantibodies is equivocal. More...
04 Jul 2013
Image: Genomic structure of HPV (Photo courtesy of the [US] National Institutes of Health).

Antibody Against HPV Protein a Potential Biomarker for Oropharynx Cancer

Antibodies against the human papillomavirus E6 protein were identified in the blood of individuals who developed oropharynx cancer as long as 10 years before onset of the disease. More...
04 Jul 2013
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.