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Clinical Chemistry

Image: Histopathology of pulmonary adenocarcinoma with prominent signet-ring cell features (Photo courtesy of Cesar A. Moran, MD).

Potential Lung Cancer Blood Biomarker Found

Patients with non-small-cell lung cancer have different profiles of metabolites in their blood, suggesting there is a way to diagnose the disease from a blood sample.  More...
04 Nov 2014
Image: Researchers have developed a simple, sensitive test for vitamin B12 deficiency that requires only a single drop of blood (Photo courtesy of Don Erhardt and the University of British Columbia).

Simple Single-Drop Test for Vitamin B12 Deficiency Developed

Researchers have developed a novel method, requiring only a single drop of blood, to test for vitamin B12 deficiency that is sensitive enough to work on anyone, including newborn babies.  More...
04 Nov 2014
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Fructose Ingestion Stimulates Hormone Leading to Fructose Tolerance Test

The determination of the body's metabolic response to fructose has been very difficult, and consequently, there is no fructose tolerance test to warn of impaired or altered fructose metabolism.   More...
04 Nov 2014
Image: The gel zymography separation of matrix metalloproteinases (MMPs) on a 7.5% polyacrylamide gel (Photo courtesy of the Italian National Research Council).

Quantitative Gel Zymography Reappraised for Matrix Metalloproteinases

A reappraisal of quantitative gel zymography technique for matrix metalloproteinases in human plasma has been used for comparison with commercially available enzyme-linked immunosorbent assay.   More...
29 Oct 2014
Image: Immunohistochemical staining of ovarian tissue with anti-CA125 for the diagnosis of ovarian carcinoma; the neoplastic cells are strongly stained (Photo courtesy of Epitomics).

Test Model Discriminates Ovarian Tumors

A new test can discriminate between benign and malignant ovarian tumors, and identify different types of carcinomatous tumors, with a high level of accuracy.  More...
28 Oct 2014
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Serum Prostate-Specific Antigen Measured by Tandem Mass Spectrometry

Prostate-specific antigen is a widely used blood test for detection and monitoring of prostate disease and many clinicians assume that all test methods produce essentially the same results, though differences do exist.   More...
23 Oct 2014

Heart Attack Biomarkers Accurate in Chronic Kidney Disease Patients

Two blood peptide biomarkers that are indicators of heart attack in the general population also provide critical information regarding heart status in chronic kidney disease patients.  More...
19 Oct 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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