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BioResearch

Targeted Drug Helps Leukemia Patients Resistant to Initial Therapy

Many patients with chronic myeloid leukemia who have not responded to interferon treatments have now been found to experience long-term benefits when switched to the targeted drug imatinib. More...
27 Mar 2012

Circadian Variation Linked to Mechanism Underlying Sudden Cardiac Death

A molecular mechanism involved in regulating diurnal variation of potassium electrical currents in heart cells has now been directly linked to abnormal cardiac repolarization and susceptibility to arrhythmogenesis. More...
27 Mar 2012
Image: A tiny crystal of mTurquoise2 viewed with a microscope. mTurquoise2 crystals were used to study the atomic scale interactions that result in its high fluorescence efficiency. (Photo courtesy of CNRS-ESRF/von Stetten/Royant).

New Fluorescent Protein Improves Sensitivity of Cellular Imaging

The sensitivity of high-resolution live cell imaging has now been much improved by a newly designed variant protein that emits turquoise light more efficiently than Enhanced Cyan Fluorescent Protein. More...
26 Mar 2012

Experimental Drug Reverses Vemurafenib Resistance in Malignant Melanoma

The experimental drug XL888 was shown to block growth of melanoma cells that had become resistant to the BRAF inhibitor vemurafenib both in vitro and in a mouse xenograft model. More...
26 Mar 2012

Enriched FAK Activity Protects Cardiomyocytes from Heart Attack Damage

Researchers have identified a protein in cardiomyocytes that when expressed at high levels protects heart cells from damage caused during myocardial infarction due to the sudden loss of oxygen. More...
22 Mar 2012

Drug Combination Cures Myeloid Leukemia in Mouse Model

The combination of the vitamin A derivative ATRA with the monoamine oxidase inhibitior tranylcypromine was shown to be an effective chemotherapeutic regimen for the treatment of acute myeloid leukemia. More...
22 Mar 2012

Silencing ROR1 Slows Breast Cancer Growth

A protein active in developing embryos but silenced in normal adult cells was found to be highly expressed in certain types of human breast cancer and may be a potential target for breast cancer therapy. More...
21 Mar 2012
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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