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BioResearch

Aurora Kinase A Prevents p53 from Inducing Stem Cell Differentiation

An oncoprotein helps maintain embryonic stem cells and induced pluripotent stem cells in the primitive pluripotent state by blocking the action of the tumor suppressor gene p53 that would otherwise induce the stem cells to differentiate. More...
22 Aug 2012

Signaling by Damaged Normal Tissues Promotes Cancer Growth and Resistance to Chemotherapy

Chemotherapy can damage normal tissues and induce cells such as fibroblasts to secrete signaling molecules that promote tumor growth and development of resistance to further drug treatment. More...
22 Aug 2012

Database Filtering Tech Leads to Synthesis of Potent New Anti-MRSA Peptides

A sophisticated computer program was designed to filter antimicrobial peptide databases in order to identify specific parameters that could be used to synthesize new and more potent drugs for treatment of infection by MRSA. More...
22 Aug 2012

Sphingosine Kinase Inhibitors Block Growth in Breast Cancer Models

Drug developers are taking a close look at inhibitors of the enzyme sphingosine kinase in the ongoing search for treatments that specifically attack cancer cells without harming normal ones. More...
21 Aug 2012

Small Molecule Kinase Inhibitors Prevent Blood Vessel Degeneration in Diabetic Retinopathy

A class of low molecular weight compounds were identified that inhibits the activity of the enzyme atypical protein kinase C and preserves the blood-retinal barrier in retinal diseases, and the blood-brain barrier in the presence of brain tumors. More...
21 Aug 2012

Bowel Cancer Linked to High Dietary Iron and Defective Gene Function

The combination of high dietary iron content and defective functioning of the adenomatous polyposis coli gene has been found to increase the risk of developing bowel cancer significantly. More...
21 Aug 2012

miRNAs Show Promise for Treatment of Ovarian Cancer

Results of a recent study suggest that microRNAs have excellent therapeutic potential, which justifies continued research efforts designed to turn them into usable anticancer agents. More...
21 Aug 2012
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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