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BioResearch

A Transcriptional Co-Repressor Protein Links Obesity to Breast Cancer Risk

Weight gain and high-carbohydrate diets increase risk of developing breast cancer due to the activity of the transcriptional co-repressor protein CtBP. More...
28 Feb 2013
Image: In this rendering, RNA-carrying "nanoliposomes" (yellow) are released from a silicon nanoparticle (grey) near targeted ovarian cancer cells (not pictured). Intravenous injections of the microscopic drug delivery system in animal models appear to have resulted in anywhere from a 36% to 83% reduction in ovarian tumor weight, depending on the dose administered (Photo courtesy of Haifa Shen and Mauro Ferrari, Methodist Hospital Research Institute).

SiRNA Nanoparticles Dramatically Reduce Ovarian Tumor Growth in Mouse Model

A specific small inhibitory RNA encapsulated in silicon nanoparticles reduced ovarian cancer growth by up to 83%, and when administered together with a chemotherapeutic drug completely stopped tumor growth. More...
28 Feb 2013
Image: Stem cell breakthrough could lead to new bone repair therapies (Photo courtesy of the University of Southampton).

Stem Cell Development Could Lead to New Nanoscale Bone Repair Technology

British scientists have created a new application to help generate bone cells that could lead to groundbreaking bone repair therapies for individuals with bone fractures or those who need hip replacement surgery due to osteoporosis and osteoarthritis. More...
27 Feb 2013

Redox Imbalance Prompts Breast Tumor Spread

Cancer researchers have found that the progression of breast tumors to a more aggressive stage with more likelihood to metastasize depends on mitochondrial complex I activity and the tumor cells' NAD+/NADH redox balance. More...
27 Feb 2013
Image: The compound TIR-199 holds much promise in the laboratory in fighting renal cancer (Photo courtesy of the University of California, Riverside).

New Agent Shows Potential in Battling Renal Cancer

Chemists have developed a substance in the laboratory that has potential applications in fighting renal cancer. More...
27 Feb 2013
Image: Kuiqpick—the new cell and tissue acquisition system from NeuroInDx (Photo courtesy of NeuroInDx).

New Cell and Tissue Acquisition Device Improves Efficiency at More Affordable Price

An innovative and affordable new cell and tissue acquisition instrument improves efficiency and ease-of-use compared to existing laser-assisted microdissection systems. More...
26 Feb 2013

Treatment with Fleeceflower Derivative Blocks Plaque Formation in Mouse Alzheimer's Disease Model

A compound derived from traditional Chinese herbal medicine prevented development of amyloid plaques when administered to young animals in a mouse model of Alzheimer's disease and reversed plaque formation when administered to older animals. More...
26 Feb 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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