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BioResearch

Novel Method Enables Isolation of Nearly Pure Population of Mammary Gland Stem Cells

The surface protein marker CD1d is highly expressed on mammary gland stem cells, and the presence of this protein was used in a novel method to isolate a remarkably pure MaSC population. More...
25 Apr 2013

Fractalkine Treatment Alleviates Symptoms of Type II Diabetes

Treatment of mouse diabetes models and in vitro cultures of human pancreatic cells with the protein fractalkine alleviated symptoms of type II diabetes by increasing insulin secretion and improving glucose tolerance. More...
23 Apr 2013

Researchers Identify Inflammation's Key Negative Regulator

Researchers working with a genetically engineered mouse model found that blocking the activity of the enzyme PDE4B suppressed inflammation by increasing the expression of the deubiquitinase enzyme CYLD. More...
23 Apr 2013

Molecular Pathways in the Hypothalamus Lead to Hypertension and Cardiovascular Disease

A recent paper linked overexpression of mTORC1 activity in the hypothalamus to the development of cardiovascular diseases. More...
23 Apr 2013
Image: Nanosponge Cross Section. Engineers at the University of California, San Diego have invented a "nanosponge" capable of safely removing a broad class of dangerous toxins from the bloodstream, including toxins produced by MRSA (methicillin-resistant Staphylococcus aureus), E Coli, poisonous snakes, and bees. The nanosponges are made of a biocompatible polymer core wrapped in a natural red blood cell membrane (Photo courtesy of Zhang Research Lab, UC San Diego Jacobs School of Engineering).

Stabilized Nanosponge Particles Sequester and Neutralize Toxins in the Bloodstream

Novel "nanosponges" comprising a biocompatible nanoparticle core coated with fragments of natural red blood cell membranes are able to absorb and neutralize a wide range of pore-forming toxins. More...
23 Apr 2013

Blocking Constant Interferon Signaling Allows the Immune System to Clear Chronic Viral Infections

Blocking constant Type I interferon signaling in mice diminished chronic immune activation and immune suppression and enabled the animals' immune system to rejuvenate and ultimately clear persistent viral infections. More...
23 Apr 2013
Image: ICM's new IBM Blue Gene/Q, code named Nostromo, will help scientists process up to 16 terabytes of Big Data per one sequence by running compute-intensive simulations at the speed of 209.7 trillion operations per second. The supercomputer will use algorithms moving beyond the "routine" sequencing of human or animal genomes, to tackle more complex processes that will reveal the rare variants in human genetics (Photo courtesy of PRNewsFoto/IBM).

Gene Supercomputer Supports Largest Biomedical Research Enterprise in Poland

A gene supercomputer has been designed to help bridge the gap between the laboratory and medical practice, gathering and processing biomedical Big Data. More...
23 Apr 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.