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BioResearch

Image: An artist’s rendering shows DNA structures and a chemical reaction “program” on the screen. A “chemical computer” executes the molecular program (Photo courtesy of Yan Liang, L2XY2.com).

Programming Language Designed to Construct Synthetic DNA

 Chemists and biotech researchers may soon be able to use a structured series of instructions to “program” how DNA molecules interact in a test tube or cell, similar to using a programming language to write computer code. More...
24 Oct 2013

New Drugs Block Synthesis of Metabolites by Nutrient-Challenged Bacteria

 Researchers have developed a new generation of antibiotics that kill bacteria by preventing them from making critical metabolites such as vitamins and amino acids. More...
24 Oct 2013
Image: This image shows a bladder tumor sample containing mutations in the STAG2 gene (Photo courtesy of the Spanish National Cancer Research Center).

Loss of STAG2 Gene Improves Bladder Cancer Prognosis

Researchers found that mutations of the STAG2 gene suppressed development of urothelial bladder cancer by acting through mechanisms that were different from the gene's role in preventing aneuploidy. More...
23 Oct 2013

Compound Found That Stops Neurodegeneration in Mice

Researchers, who in 2012 identified a key pathway leading to brain cell death in mice, have used an orally administered compound to block that pathway, preventing neurodegeneration in the lab mice. More...
23 Oct 2013
Image: This study showed that the drug benztropine led to the repair of multiple sclerosis-damaged nerve fibers in animal models (Photo courtesy of Dr. Luke Lairson, The Scripps Research Institute).

Benztropine Reverses Multiple Sclerosis in Animal Models

 Autoimmune disease researchers have reported the successful use of the Parkinson's disease drug benztropine [benzatropine (INN)] for treatment of animal models of multiple sclerosis. More...
22 Oct 2013

Collaboration to Use Big Data to Predict Malaria Outbreaks and Dengue Fever

Scientists are collaborating to battle infectious diseases and other illnesses in real-time with better data applications for public health.  More...
22 Oct 2013
Image: T-cells (red) are activated more robustly when they interact with artificial antigen-presenting cells (green) that are elongated (right) versus round (left) (Photo courtesy of Dr. Karlo Perica, Johns Hopkins University).

T-cells Activated More Effectively by Ellipsoidal Artificial Antigen-Presenting Cells

Artificial antigen-presenting cells shaped like American footballs were able to activate immune system T-cells to attack and destroy cancer cells much more effectively than spherical aAPCs. More...
21 Oct 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.