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BioResearch

Image: Soft micellar nanoparticles can be prepared from DNA conjugates designed to assemble via base pairing such that strands containing a polymer corona and a cholesterol tail generate controlled supramolecular architecture (Photo courtesy of Nanoscale).

Nanomolecular Agents Deployed to Detect Diseases

Pharmaceutical sleuthing has come closer to reality with the development of “nano-spy” compounds programmed to jump into play when they receive a specific signal.  More...
22 Jan 2014
Image: Three-dimensional molecular space-fill model of tetrabenazine (TBZ) (Photo courtesy of Wikimedia Commons).

Results of Mutagenesis Study Expected to Guide Development of Drugs for Nervous System Disorders

A mutagenesis study utilizing a human gene expressed by yeast cells has yielded new insights into the molecular mechanism controlling binding of neurotransmitters in the brain.  More...
21 Jan 2014

Living Brain Cells Generated from Biobanked Brain Tissue

Scientists for the first time have generated induced pluripotent stem cells lines from non-cryoprotected brain tissue of Alzheimer’s disease patients.  More...
21 Jan 2014
Image: Virus-infected cells after treatment with Vecoy nanoparticles (indicated by arrows) (Photo courtesy of Vecoy Nanomedicines).

Nanoparticle Traps Represent a Radical New Method for Treating Viral Infections

An Israeli biotechnology start-up company is researching a radically different approach to the problem of preventing and curing viral infections.  More...
20 Jan 2014

Stimulating Brain Cells Using Optogenetics Stops Binge Drinking

Researchers are using a new strategy to change alcohol-drinking behavior in lab rats, using new optogenetic technology that uses light to stimulate neurons.  More...
20 Jan 2014
Image: Scanning electron micrograph of a melanoma cell. BRAF fusion genes in pan-negative melanomas may render them sensitive to MEK inhibitors (Photo courtesy of Vanderbilt University).

Gene Fusions Make Some Pan-Negative Melanomas Sensitive to MEK Inhibitors

Cancer researchers have identified a class of fusion genes that drive melanoma metastasis in the 35% of these skin cancers that lack the previously known driver mutations.  More...
16 Jan 2014

Blocking RON Shuts Down Breast Cancer Metastasis

A recent paper suggested that initiation of breast cancer metastasis did not depend on a specific genetic mutation but rather on improper regulation of molecular pathways that control activation and inactivation of certain critical genes.  More...
16 Jan 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.