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BioResearch

Image: Molecular model of the enzyme phosphoenolpyruvate carboxykinase (PEPCK) (Photo courtesy of Wikimedia Commons).

Cancer Researchers Identify Enzyme That Enables Glucose-Independent Tumor Growth

Cancer researchers have identified an enzyme that allows tumor cells to exploit alternative energy sources in order to survive when sources of glucose have been depleted.  More...
01 Nov 2015

American-British Cooperation to Establish New Drug Discovery Company

An American biotechnology venture capital company is providing initial funding for the establishment of a drug development firm that will operate in the framework of a prestigious British research institution.  More...
01 Nov 2015
Image: A schematic diagram of a new method that rapidly analyzes the RNA (green strands) of HIV for mutations (red dot) that convey drug resistance. The system does not require transcription of RNA to DNA, as current technologies do, and works within one solution (purple droplet) (Photo courtesy of Dr. Lei Zhang, Brown University).

One-Tube RNA Ligation and Amplification Method for Rapid Detection of Drug Resistant HIV

By not requiring transcription of RNA to DNA, a novel one-tube method allows the rapid detection of drug resistant strains of HIV.  More...
28 Oct 2015
Image: Neutrophils produce bacteria-ensnaring NETs (shown in blue/green) in response to tamoxifen treatment (Photo courtesy of the University of California, San Diego).

Neutrophil Activation Underlies Cancer Drug's Antibacterial Effect

The bactericidal properties of the cancer drug tamoxifen have been linked to its modulation of sphingolipid biosynthesis and the effect this has on neutrophil activation and the generation of antimicrobial neutrophil extracellular traps.  More...
28 Oct 2015
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DNA Enrichment Increases Usefulness of Liquid Biopsy Technology

DNA enrichment technology was a critical tool used in a study that detected genetic variations in circulating tumor cells in blood samples from non-small-cell lung cancer patients.  More...
27 Oct 2015
Image: Space-filling model of the alpha-B-crystallin protein. The hexameric subunit is indicated in color (Photo courtesy of Dr. Andi Mainz, Technical University of Munich).

Solid State NMR Reveals Heat Shock Protein's Molecular Structure

A team of German proteomics researchers has established the molecular structure of the small heat shock protein alpha-B-crystallin, a finding that is expected to aid in the search for drugs to treat illnesses such as Alzheimer's disease, which are characterized by toxic protein clumping.  More...
26 Oct 2015

Agreement Enlarges China's Role in Cancer Immunotherapeutics Development

A recent agreement marks the expansion of drug development collaboration between a Chinese biopharmaceutical company and a major international drug corporation.   More...
26 Oct 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.