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BioResearch

Image: A schematic illustration of the liquid-metal nano-terminators (left). The red spheres are the anticancer drug doxorubicin. A representative TEM image of the liquid-metal nano-terminators (right) (Photo courtesy of North Carolina State University).

Biodegradable Metallic Nanodrops for Safe Cancer Drug Delivery

A novel drug delivery system based on liquid metal nanodrops was used to safely transport the highly toxic chemotherapeutic agent doxorubicin into the cancer cells comprising ovarian tumors in a mouse xenograft model.  More...
14 Dec 2015
Image: Investigators at Kyoto University have demonstrated the potential of a PD-1 antibody, nivolumab, to treat platinum-resistant ovarian cancer (Photo courtesy of Kyoto University).

Nivolumab Found Safe and Effective in Ovarian Cancer Phase II Trial

A team of Japanese cancer researches has demonstrated the safety and effectiveness of the drug Nivolumab for treating women with platinum-resistant ovarian cancer.  More...
13 Dec 2015
Image: Ribbon representation of a repeating unit in the extracellular E-cadherin ectodomain (Photo courtesy of Wikimedia Commons).

Tumors Grow When Normal Cells Are Induced to Become Cancerous

A recent study determined how the cancer cells within a tumor promote its growth by transforming neighboring normal epithelial cells into cancer cells.  More...
13 Dec 2015

Drug Development Agreement Targets Migraine Treatments

A British drug development company is teaming up with a major international pharmaceutical corporation to develop, commercialize, and manufacture treatments for migraine.  More...
13 Dec 2015
Image: SBI-756, a first-in-class compound, halts melanoma growth by disrupting protein production (Photo courtesy of Sanford Burnham Prebys Medical Discovery Institute).

Candidate Melanoma Drug Disrupts Translation Initiation Factor Complexes

A potentially game changing drug for the treatment of malignant melanoma works by breaking up the translation initiation complexes that the cancer cells require in order to translate mRNA into proteins.  More...
09 Dec 2015
Image: Polarized fluorescent micrograph showing hepatocytes generated by the upcyte technique (Photo courtesy of Dr. Yaakov Nahmias, Hebrew University of Jerusalem, Israel).

Cultured Liver Cells Now Available for Research Applications

An advance in cell culture technology will enable researchers to maintain liver cells in culture for up to 40 replication cycles, which will provide important study material for research, clinical applications, and pharmaceutical development.  More...
08 Dec 2015
Image: Novel, low-cost nanoprisms are capable of detecting microRNAs at attomolar concentrations (Photo courtesy of the Department of Chemistry and Chemical Biology, School of Science, Indiana University-Purdue University Indianapolis).

Plasmon Resonance-Based Nanosensor Detects Minute Levels of Pancreatic Cancer-Related MicroRNA

Measurement of levels of specific microRNAs in various cell or bodily fluids can now be carried out using an ultrasensitive surface plasmon resonance-based nano-sensor.   More...
08 Dec 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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