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BioResearch

Image: Atorvastatin bound to HMG-CoA reductase (Photo courtesy of Wikimedia Commons).

Statins Slow Growth of Cancers with p53 Structural Mutations

Cancer researchers have demonstrated the ability of cancer-lowering statin drugs to slow the growth of certain types of cancers with p53 mutations. More...
08 Feb 2017
Image: Researchers have synthesized an antisense oligonucleotide (ASO) that can lower tau levels and prevent some neurological damage. In neurons that contain the ASO (above, in red) there are no tau tangles (in green) (Photo courtesy of Dr. Sarah DeVos, Washington University School of Medicine).

Antisense Therapy Lowers Levels of Pathogenic Tau Protein in Models

Antisense therapy was used to reverse the damage caused by accumulation of tau protein in mouse and monkey models of neurodegenerative diseases. More...
08 Feb 2017
Image: Tiny, painless microneedles on a patch can deliver insulin in response to rising glucose levels (Photo courtesy of the ACS).

New Approach to Diabetes Based on Microneedle Smart Patch Insulin Delivery

A novel "microneedle smart patch" has been developed that was designed to automatically correct glucose imbalance in patients with type I or advanced type II diabetes. More...
02 Feb 2017
Image: A ball-and-stick model of the aurintricarboxylic acid (ATA) molecule (Photo courtesy of Wikimedia Commons).

Aurintricarboxylic Acid Proposed as Basis of New Glioblastoma Treatment Plan

The compound aurintricarboxylic acid (ATA) has been identified as a possible new therapeutic agent for treatment of patients with the deadly brain cancer glioblastoma multiforme (GBM). More...
01 Feb 2017
Image: Human placental cell line Jeg-3 can be readily infected by a circulating strain of Zika virus (left panel) and completely protected by treatment with nanchangmycin (right panel). All cells are shown in blue while virally infected cells are stained in green (Photo courtesy of Dr. Sara Cherry, University of Pennsylvania).

Nanchangmycin Prevents Zika and Related Viruses from Infecting Cells

Several low molecular weight drugs have been identified that demonstrate promising effectiveness for blocking infection by Zika and other related viruses. More...
31 Jan 2017
Image: A colorized scanning electron micrograph (SEM) depicting mitochondria, which play a critical role in peripheral nerve growth regeneration (Photo courtesy of Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego).

Neurite Outgrowth Stimulated by Blocking Acetylcholine Receptor

Neurosciences researchers have found that blocking the muscarinic acetylcholine type 1 receptor (M1R) in neurons promotes neurite outgrowth, which prevents or reverses peripheral neuropathy in cell and rodent models of type I and II diabetes, chemotherapy-induced neuropathy, and HIV. More...
31 Jan 2017

Bacteriophage Infection Mediated by Molecules from Susceptible Organisms

A team of Israeli molecular microbiologists has found that bacteria that are resistant to infection by bacteriophages can lose this resistance when incubated together with susceptible bacteria. More...
26 Jan 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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