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BioResearch

Image: Researchers have developed hybrid bacteriophage particles that could broaden the range of target bacteria (Photo courtesy of Tel Aviv University).

Novel Method Extends Range of Bacteriophage-based Applications

A team of Israeli molecular microbiologists developed a method for extending the host specificity of bacteriophage particles to enable them to transfer DNA into a wide range of pathogenic bacteria. More...
04 Jul 2017

Medicinal Shrub Shows Potent Anti-Alzheimer's Disease Potential

Extracts from stem, leaves, and root of the African medicinal shrub Carpolobia lutea were found to possess inhibitors of the enzyme acetylcholinesterase (AChE) and antioxidants, which indicate potential for development as a treatment of Alzheimer’s disease (AD) and other disorders characterized by a cholinergic deficit. More...
03 Jul 2017
Image: Three-dimensional photomicrograph of a tumor showing Tregs (green), blood vessels (red) and tumor matrix (blue) (Photo courtesy of the Vignali Laboratory, University of Pittsburgh School of Medicine).

Study Results May Help Improve Cancer Immunotherapy

Cancer researchers have shown how the activity of a specific protein enables regulatory T-cells (Tregs) to protect tumors from the immune system's natural tracking and killing response. More...
29 Jun 2017
Image: A photomicrograph of human breast cancer line MCF-7 cells (Photo courtesy of Wikimedia Commons).

Transcription Factor Deficit Spurs Tumor Development

A team of British cancer researchers found that the transcription factor proline-rich homeodomain protein (PRH/HHEX) played a tumor suppressive role in the breast, and they provided an explanation for the finding that low PRH mRNA levels were associated with a poor prognosis in breast cancer. More...
28 Jun 2017
Image: Research of broccoli extract shows potential as diabetes treatment (Photo courtesy of Margareta Gustafsson Kubista, University of Gothenburg).

Broccoli Extract Shows Potential as Diabetes Treatment

Research carried out with animal models and with an obese human population has shown that a natural constituent of certain types of cruciferous plants has potential for treating type II diabetes. More...
27 Jun 2017
Image: A photomicrograph of a cross section of a mouse aorta, the main artery in the body, with a large plaque. Straight red lines toward the upper left are the wall of the aorta. Yellow areas are where housekeeping cells called macrophages are clearing cellular waste (Photo courtesy of Ismail Sergin, Washington University School of Medicine).

Trehalose Boosts Macrophage Ability to Clear Plaques

Cardiovascular disease researchers working with mouse models have found that treatment with the sugar trehalose boosts the activity of the macrophages responsible for clearing the molecular and cellular debris that make up atherosclerotic plaques. More...
22 Jun 2017
Image: The structure of the obscurin protein encoded by the OBSCN gene (Photo courtesy of Wikimedia Commons).

Gene Mutation Leads to Hypertrophic Cardiomyopathy

A team of heart disease researchers explained how a mutation in the gene coding for the obscurin family of proteins leads to the development of an enlarged heart, a condition known as hypertrophic cardiomyopathy. More...
21 Jun 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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