BioResearch
New Chemical Cocktail Enables Study of Totipotent Stem Cells
A team of developmental molecular biologists has formulated a chemical cocktail that enables the derivation of stem cells with unique functional and molecular features from mice and humans including the ability to maintain a state of totipotency that allows them to develop into extra-embryonic tissues such as placenta. More...19 Apr 2017
X-Ray Crystallography Findings Aid Discovery of New Drugs
Sensitive X-ray crystallography techniques were used to determine the three-dimensional (3D) molecular structure of the Mycobacterium tuberculosis enzyme RNA polymerase (Mtb RNAP) alone and when bound to the present first-line anti-tuberculosis drug rifampin. More...18 Apr 2017
Cancer Growth Influenced by Myosin and FAK Protein Interaction
A team of cancer researchers has found that the interaction between the myosin and FAK (Focal adhesion kinase) proteins is critical to the ability of cancer cells to grow and spread to sites distant from that of the primary tumor. More...13 Apr 2017
Cholesterol-Lowering Small RNA Drug Shows Promise in Early Trial
Results of a phase II, multicenter, double-blind, placebo-controlled, multiple-ascending-dose clinical trial confirmed that the experimental small interfering RNA (siRNA) drug inclisiran was effective for treating patients with elevated LDL cholesterol levels who were at high risk for developing cardiovascular disease. More...12 Apr 2017
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In Other News
Fruit Fly Model Used to Detect Proteins Coded by Circular RNAs
Cryomicroscopy Enhances Mapping of Cystic Fibrosis Protein
Heating Method Developed for Rapid Delivery of Macromolecules
Nanoscale Device Developed for Separation of NA Mixtures
Elevated Methylthioadenosine Levels Linked to Poor Sepsis Prognosis
Paper-Based Battery Powers Microfluidic Devices
Drugs Identified May Stimulate Axon Regeneration
RA Drug Blocks Growth of PTEN-Mutant Cancers
Stem Cell Structure to Facilitate In Vitro Embryonic Studies
Biomechanical Stress and Inflammation Linked Using Muscle Cells
Black Carbon Nanoparticles Modify Pathogens and Affect Resistance
Miniaturized Gene Editing for Treatment of Macular Regeneration
Genetic Remodeling Transforms E. Coli into Intestinal Pathogen
Researchers Define Autoantibody-Producing Role of B-Cells in RA
Collagen Deposition-Promoting Gene Linked to Cancer Metastasis
Metabolic Glycoengineering Introduces Targets for Guided Drug Treatment
Novel Culture Method for Activation of Cancer-Fighting T-Cells
Review Focuses on Lipid Nanoparticles as Gene Therapy Carriers
Reprogrammed Liver Cells Replace Nonfunctional Pancreatic Cells in Mouse Model
Assay Determines Suitability of Nanoparticles for In Vivo Use
Novel Method Enables Generation of Thyroid Tissue from Mouse Stem Cells
Cancer Researchers Identify Factors That Drive Melanoma Metastasis
Stem Cell Therapy is Safe: Reprogramming Does Not Increase the Rate of Mutagenesis
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
