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BioResearch

Image: The molecular structure of the human cystic fibrosis protein, which controls the flow of crucial ions in and out of cells (Photo courtesy of the Laboratory of Membrane Biology and Biophysics at The Rockefeller University).

Cryomicroscopy Enhances Mapping of Cystic Fibrosis Protein

A recent paper detailed the three-dimensional (3D) structure of cystic fibrosis transmembrane conductance regulator, the protein responsible for the genetic disorder cystic fibrosis (CF). More...
05 Apr 2017
Image: A scanning-electron microscope (SEM) image of chemically-fixed HeLa cancer cells on the gold nanopyramid substrate. Following nanosecond laser pulses, the tips of the pyramids create tiny holes in the cell membranes, allowing molecular cargo to diffuse into the cells (Photo courtesy of Harvard University).

Heating Method Developed for Rapid Delivery of Macromolecules

A team of cancer researchers developed a precise and controlled mechanism that rapidly introduces molecules as large as proteins or nucleic acids into living cells. More...
04 Apr 2017
Image: Ultrafast electrophoretic microRNA extraction from a nucleic acids mixture using quartz nanopillars of 250-nanometer diameter arrayed inside a 100-nanommeter high nanoslit region (Photo courtesy of Dr. Noritada Kaji, Nagoya University).

Nanoscale Device Developed for Separation of NA Mixtures

A team of Japanese engineers has developed a nanoscale device for the rapid separation of microRNA (miRNA) from mixtures of miRNA, RNA, and DNA. More...
24 Mar 2017
Image: Bacteria (yellow) interact with a human white blood cell. If left unchecked, this encounter might develop into sepsis (Photo courtesy of the NIAID).

Elevated Methylthioadenosine Levels Linked to Poor Sepsis Prognosis

A recent study showed that methylthioadenosine, substrate of the methionine salvage pathway, was a regulator of sepsis that could accurately predict prognosis in patients. More...
23 Mar 2017
Image: A hydraulic battery pumping fluid through a simple microchannel at a constant rate of 0.6 microliters per minute. Each snapshot is 12 minutes apart (Photo courtesy of the University of North Carolina).

Paper-Based Battery Powers Microfluidic Devices

A team of biomedical engineers has developed a novel type of "hydraulic battery" that uses inexpensive, minute paper pumps to power the movement of liquids, including biological fluids, through portable microfluidic diagnostic or analytical devices. More...
22 Mar 2017
Image: Treatment with fusicoccin-A induces the regeneration of damaged axons towards the center of the injury. The axons are stained in green and the tips of the growing axons, called growth cones, are stained in red (Photo courtesy of McGill University).

Drugs Identified May Stimulate Axon Regeneration

A team of neurological science researchers has identified a class of small molecular growth promotors that may prove to be the basis for drugs designed to correct loss of axons following brain or nervous system injury or other disorders and diseases, including multiple sclerosis and neurodegenerative conditions. More...
21 Mar 2017

RA Drug Blocks Growth of PTEN-Mutant Cancers

Cancer researchers have found that a drug approved for treatment of rheumatoid arthritis may block the growth of PTEN-mutant tumors by inhibiting the enzyme dihydroorotate dehydrogenase. More...
17 Mar 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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