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BioResearch

Image: C. mastitidis is a commensal bacterium living on the surface of the eye (Photo courtesy of Dr. Rachel Caspi and Dr. Anthony St. Leger, National Eye Institute).

Beneficial Eye Bacteria Helps Prevent Infection

A team of microbiologists identified Corynebacterium mastitidis as a commensal bacterium living in the conjunctiva of the eye where it induces the production of interleukin (IL)-17, a signaling protein critical for host defense. More...
26 Jul 2017
Image: A cell in the process of dividing (center) that is being engulfed by cells on either side. DNA is shown in blue and a protein responsible for attachment between cells is shown in green (Photo courtesy of Dr. Jo Durgan, Babraham Institute).

Cell Cannibalism May Lead to Cancer Control Therapy

An unexpected link between cell division and cell cannibalism (entosis), which is relevant to both cancer and chemotherapy, was described in a recent paper. More...
25 Jul 2017
Image: Researchers are hoping to use nanotechnology to develop more targeted treatments for bacterial infections. In this illustration, an antimicrobial peptide is packaged in a silicon nanoparticle to target bacteria in the lung (Photo courtesy of Jose-Luis Olivares, Massachusetts Institute of Technology).

Nanoparticle Treatment Cures Bacterial Infection in Model

A novel approach for treating bacterial infections is based on the use of porous silicon nanoparticles to transport a combination of bactericidal peptides, which penetrate the cell membranes of Gram-negative bacteria and kill them with minimal unpleasant side effects. More...
24 Jul 2017
Image: Arterial endothelial cells derived from human pluripotent stem cells express activated NOTCH1 (in red, which is an arterial endothelial cell marker) and CD144 (in white, which is a pan endothelial cell marker) (Photo courtesy of the Morgridge Institute for Research).

Stem Cells Used to Generate Functional Arterial Endothelial Cells

A team of cardiovascular disease researchers developed a method for using human pluripotent stem cells to generate fully functional arterial endothelial cells, which are vital for vascular development and disease research. More...
20 Jul 2017
Image: Researchers have solved the structure of the NS1 protein that helps the common respiratory virus RSV evade the immune system (Photo courtesy of Dr. Daisy Leung, Washington University School of Medicine).

RSV Non-Structural Protein Interferes with Host Immune Response

A team of molecular virologists used X-ray crystallography to establish the structure of a protein that enhances the infectivity of respiratory syncytial virus (RSV) by interfering with the host's immune response. More...
19 Jul 2017
Image: A representation of the Cpf1 protein in complex with its target RNA and target DNA (Photo courtesy of the University of Copenhagen).

Structural Analysis Explains Action of New Gene Editing Tool

An alternative approach for editing of double-stranded DNA may prove to be more versatile than the currently popular CRISPR/cas9 gene editing technique. More...
18 Jul 2017
Image: New 3D printing technologies allow researchers to create patient-specific heart valve models that mimic the physiological qualities of the real valves. This image shows the submerged valve during flow testing (Photo courtesy of the Georgia Institute of Technology).

3D-Printed Heart Valve Models Mimic Physiology

Cardiovascular disease researchers used an advanced multi-material three-dimensional printing technique to create patient-specific heart valve models that mimic the physiological qualities of human valves. More...
17 Jul 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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