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BioResearch

Image: Brightfield images of day 50 LBO-derived Matrigel colonies from RUES2 cells (Photo courtesy of the Snoeck Laboratory at Columbia University Medical Center).

Novel Model Systems Assist Lung Disease Studies

Lung organoids generated from human pluripotent stem cells were shown to recapitulate lung development and were posited as potentially useful tools to model lung disease. More...
25 May 2017
Image: New research identified the function of the lncRNA SPRIGHTLY in skin cancer (Photo courtesy of the Sanford Burnham Prebys Medical Discovery Institute).

Cancer Organizational Role Established for Non-Coding RNA

An organizational role linked to cancer formation and growth has been established for the long non-coding RNA known as SPRIGHTLY. More...
24 May 2017
Image: The FlexLISA kit provides a flexible tool for development and optimization of sandwich ELISA assays (Photo courtesy of Innova Biosciences).

New Kits Designed for ELISA Assay Development

A novel line of kits for the development and optimization of sandwich ELISA assays is now available for biotech and other life science researchers. More...
23 May 2017
Image: When free C3d vaccine was added to a tumor, the cancer cells began to die (right). Tumor cells not given the vaccine continued to grow (Photo courtesy of the University of Michigan).

Protein Fragment Promotes Anti-Cancer Response

Free C3d protein, a fragment of the third component of complement, has been found to prevent cancer cells from avoiding the body's immune response and has potential to be developed into a chemotherapeutic agent for cancer treatment. More...
22 May 2017
Image: A recent study found that about 6,500 genes are expressed differently in men and women (Photo courtesy of the Weizmann Institute of Science).

Gene Expression Suggests Sexes Evolve Differently

A team of molecular geneticists has found that a large number of genes are expressed differently in men and women, which begins to explain why that despite sharing almost identical genomes the two sexes are distinctly dimorphic, with dissimilar disease susceptibilities and mutation rates. More...
18 May 2017
Image: At the center of the image is an optic nerve with glaucoma damage, signified by loss of color and a round rim of pink tissue within the nerve (Photo courtesy of Carla J. Siegfried, Washington University School of Medicine).

Biomarker Traces Glaucoma Development and Progression

A potential biomarker protein has been identified that was elevated in rodent models of glaucoma and in fluid taken from the eyes of human patients with the disease. More...
17 May 2017
Image: Neurons from Angelman syndrome (AS) patients lack expression of the UBE3A protein due to an epigenetic defect. The photomicrograph shows that a new method restored normal expression of the UBE3A protein in neurons derived from the cells of an AS patient by correcting the aberrant methylation pattern (Photo courtesy of the Salk Institute for Biological Studies).

Artificial Editing Technique Modifies Gene Activity

A team of molecular biologists has developed an artificial epigenetic editing technique that adds methyl groups to DNA and modifies specific gene activity in a hereditary manner. More...
16 May 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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