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BioResearch

Gene Therapy Successfully Treats Emphysema in Mouse Model

Gene therapy has been used successfully to treat the inherited form of emphysema caused by human alpha-1 antitrypsin deficiency in a mouse model of the disease. More...
06 Jan 2010

Intracellular pH Determines How Cystic Fibrosis Protein Regulates Ion Transport

The protein cystic fibrosis transmembrane conductance regulator is responsible for maintaining the ion channels that move chloride ions and water into and out of cells, and mutations that prevent correct CFTR functioning can lead to the build up of the thick mucous that characterizes cystic fibrosis. More...
06 Jan 2010
Image: A stylized scanning electron microscopic image of mycobacterium tuberculosis (Photo courtesy of Medical RF.com).

Interferon-Gamma Pathway Activates the Immune System Against Tuberculosis

A recent study revealed the molecular mechanism whereby interferon-gamma regulates the immune response that protects the body from the bacterium that causes tuberculosis, Mycobacterium tuberculosis. More...
05 Jan 2010

Gene Silencing Reduces Metastatic Potential of Melanoma Tumors

Cancer researchers used small hairpin RNA to silence the gene in melanoma cells that encodes the transcription factor E2F1 and found that this treatment reduced the potential for metastasis without modifying the tumor's ability to grow. More...
05 Jan 2010

Ion Channel Protein Linked to Blood Pressure Regulation

In mammals, short-term control of blood pressure is maintained by molecular complexes known as baroreceptors, which require the activity of a particular ion channel to function correctly. More...
04 Jan 2010

Promising Cancer Drug Cordycepin Works by Inhibiting Protein Synthesis

A recent study provides new information regarding the mode of action of the promising anticancer drug cordycepin. More...
04 Jan 2010

Sleep Deprivation Disrupts cAMP Signaling in the Brain's Hippocampus

The effects of sleep deprivation, which include forgetfulness, impaired mental performance, and a decline in the ability to learn, are modulated at the molecular level by changes in the metabolism of 3', 5'-cyclic AMP in the hippocampus region of the brain. More...
31 Dec 2009
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.