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BioResearch

Image: A scanning electron micrograph (SEM) showing the morphology of the bright and round shaped exosomes (Photo courtesy of the University of California, San Diego).

Transferred MicroRNAs Modulate Insulin Sensitivity in Models

Studies using mouse models revealed that certain microRNAs (miRNAs) capable of modulating glucose metabolism were transferred via exosomes from adipose tissue macrophages to insulin target cells where they induced insulin resistance or sensitivity. More...
02 Oct 2017
Image: Graphics from a new fluorescent sensor, showing changes in GTP levels following administration of the drug MPA (Photo courtesy of Roswell Park Cancer Institute).

Genetically Encoded Sensors Determine Intracellular GTP Levels

A new class of genetically encoded sensors is able to rapidly detect changes in GTP (guanosine-5'-triphosphate) levels in living cells. More...
28 Sep 2017
Image: After the lids are deposited onto the cups, the particles are heated slightly to form a tight seal between the lids and cups (Photo courtesy of the Langer Lab).

Drug Delivery Method Used with Hollow Microstructures

A new method for producing microstructures was used to create hollow injectable microparticles that could be filled with liquid containing a therapeutic agent and then degraded over a programmable time period. More...
27 Sep 2017
Image: A photomicrograph of chromosomes in uncondensed form (left) and condensed form in dividing cell (right) (Photo courtesy of Dr. Kenneth Zaret, University of Pennsylvania).

Study Shows Cells Maintain Active Gene Expression during Mitosis

A team of cell biologists has found that contrary to commonly held theory, gene expression continues during the process of cell division (mitosis). More...
27 Sep 2017
Image: The human leukocyte antigen (HLA) ligand for a Killer-cell immunoglobulin-like receptor (KIR) (Photo courtesy of Wikimedia Commons).

Novel Vaccine Could Simultaneously Target Multiple Viral Infections

A novel vaccine designed to prevent infection by several different viruses simultaneously in based on ability of a receptor protein on the surface of immune cells to recognize a common, invariable viral antigen. More...
26 Sep 2017
Image: A transmission electron micrograph (TEM) of a number of Lassa virus virions adjacent to some cell debris. The virus, a member of the virus family Arenaviridae, causes Lassa fever (Photo courtesy of the CDC).

Monoclonal Antibody-based Vaccine Prevents Lassa Fever in Model

A combination of human monoclonal antibodies was used to protect monkeys infected with Lassa fever virus and prevented infection even when administered as late as eight days after exposure to the virus. More...
22 Sep 2017
Image: A modified three-dimensional printing technique was used to create temporary microstructures that could be degraded on demand using a biocompatible chemical trigger (Photo courtesy of the Wong Laboratory, Brown University).

3D Printing Used to Create Degradable Microfluidic Devices

A team of bioengineers modified the stereolithographic three-dimensional printing technique to create a series of microfluidic devices from biocompatible and degradable materials. More...
21 Sep 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.