Personal Cell Analysis System Monitors Treatment of HIV/AIDS

A new system, based on the personal cell analysis platform (PCA) platform, is designed for diagnosis and monitoring human immunodeficiency virus infections.

Dubbed the AutoCD4/CD4% system, it includes new automated gating and acquisition software and a single antibody cocktail. Designed specifically to meet the needs and challenges of a broad population of users, the easy-to-use software allows operators with minimal technical expertise to monitor a patient's T-lymphocytes accurately and effortlessly.

From a single assay, a technician can get a patient's CD4 count, total lymphocyte count, and CD4% value with only 10 µl of whole blood, and acquire results with just one click of a button. The CD4% value is particularly critical for pediatric patients.

The new software also includes an error detection feature and easy-to-read results in the form of individual patient as well as summary reports. These features help ensure reproducible, high quality test results from every sample.

Guava Technologies, Inc. (Stamford, UK) launched Guava AutoCD4/CD4% system with the expectation that it will help fight the global AIDS pandemic. "Access to appropriate diagnostic tools is crucial in the battle against HIV/AIDS, and we are committed to developing our clinical cell analysis technology so that it is truly accessible to those who need it anywhere in the world," said Larry Bruder, president & CEO of Guava Technologies. "We designed our AutoCD4/CD4% system so that any healthcare professional-even one without prior experience with flow cytometry-can get accurate and reliable test results every time."

The patented microcapillary design eliminates the need for complicated fluidics making Guava Instruments ideally suited for use anywhere in the world, even in remote regions. They are more compact and have fewer moving parts than most traditional flow cytometers. They also accommodate smaller sample volumes, have lower reagent demands, and generate less waste. Guava Software guides the user through whatever procedure is being conducted, whether it is an assay, instrument setup, or routine maintenance.

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