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Molecular Probes Licenses Fluorescence Technology to LightUp

By HospiMedica staff writers
Posted on 24 Apr 2003
New DNA typing assays using fluorescence-based technology licensed from Molecular Probes (Eugene, OR, USA) are being launched by LightUp Technologies AB (Huddinge, Sweden).

These new assays, called LightUp Probes, can be used to identify and quantify the presence of bacteria, viruses, and other pathogens by detecting and analyzing DNA. Molecular Probes will supply advanced fluorescent stains for the assays that increase sensitivity in detecting DNA and other nucleic acids. The LightUp Probes are short peptide nucleic acid conjugates that increase in fluorescence when hybridized to target sequences. The technology is useful for identifying and quantifying targets in an extremely rapid, one-step homogenous hybridization assay. It can be used on its own or in combination with polymerase chain reaction (PCR).

"The combination of our innovative DNA typing technology and Molecular Probes' proprietary fluorescent stains is truly synergistic,” said Ulrica Sehlstedt, Ph.D., CEO of LightUp Technologies. "When enhanced with Molecular Probes' fluorescent stains, our LightUp Probes make DNA assays, including those using real-time PCR, even more sensitive, enabling their use in a wide variety of applications.”




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