Nova Biomedical Launches New BioProfile FLEX2 On-Line Autosampler

Nova Biomedical (Waltham, MA, USA) has launched the BioProfile FLEX2 On-Line Autosampler (OLS), a modular system that connects as many as 10 bioreactors to one FLEX2 analyzer for up to three weeks of walkaway, automated sampling, analysis, and feedback control of key cell culture analytes. The FLEX2 measures up to 16 tests, including pH, gases, metabolites, osmolality, cell density, and cell viability.

Nova develops and manufactures state-of-the-art, whole blood point-of-care and critical care analyzers, as well as the most advanced instruments for cell culture monitoring in the biotechnology market. Nova’s biosensor technology is incorporated in its products ranging from handheld meters for glucose self- and point-of-care testing to critical care whole blood analyzers for the rapid measurement of over 20 analytes. Nova’s biotechnology-specific BioProfile line has pioneered comprehensive cell culture testing, providing over 16 critical cell culture tests with 12 unique instrument offerings for a broad range of cell culture applications.


Nova’s FLEX2 combines its MicroSensor Card chemistry technology with optical measurements and freezing point osmometry to offer an automated and comprehensive cell culture analyzer that eliminates chemistry sensor maintenance, increases analyzer speed, and reduces sample volume. With the OLS, FLEX2 uses a small sample volume of 5.6 mL for the 16-test assay to allow frequent sampling for this detailed look at culture performance. Up to 24 samples per day for each of 10 bioreactors can be analyzed in as fast as six minutes, with proven comparability to manual sampling. The OLS provides automated sampling, analysis, and feedback control of 10 bioreactors in as fast as one hour for chemistry results, with only 20 minutes needed for setup. The ability of OLS and FLEX2 to provide unaided capture of key cell culture attributes across 10 bioreactors saves hours of scientists’ time versus manual sampling and analysis, and eliminates after-hours cell culture monitoring.

“We are excited to launch the next addition to the BioProfile FLEX2 platform with the On-Line Autosampler. FLEX2 OLS represents the latest in cell culture automation technology and further demonstrates Nova’s leadership and history of innovation,” said Matt McRae, sales product line manager at Nova.

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