Profiling Service Tracks Proteins Involved in Cell Growth

A proteomics signal transduction protein profiling service tracks proteins involved in cell growth and proliferation.

The Kinetworks cell cycle screen uses only validated antibodies and is a cost-effective solution for researchers to detect up to 30 cell cycle proteins in their model system with high reproducibility, accuracy, and speed. Cell cycle control has implications for the development of therapies to treat diseases such as cancer that involve uncontrolled cell growth. Kinetworks is the product of Kinexus Bioinformatics Corp. (Vancouver, Canada).

Kinexus also offers screening services for the detection of 75 protein kinases, 33 phosphoproteins, 25 phosphatases, 25 apoptosis, and 25 stress/heat shock proteins using as little as 300 micrograms of total cell or tissue lysate protein. The screening services have many applications, including the identification of drug targets, disease diagnostic markers, new research leads, and characterization of drug candidates for mechanisms of action and toxicity.

"By adopting a systems biology approach, our Kinetworks multi-immunoblotting service has proven instrumental in uncovering changes in important signaling proteins in several experimental model systems and disease states,” said Dr. Steven Pelech, president and CEO of Kinexus and a professor of medicine at the University of British Columbia (Vancouver, Canada).




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