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SNP-Based Whole-Genome Linkage Scans

By Biotechdaily staff writers
Posted on 24 Jun 2002
A new service enables researchers to conduct single nucleotide polymorphism (SNP) whole-genome linkage scans that can facilitate the identification of specific locations on the genome associated with traits of interest.

Identifying loci associated with traits of interest is a critical first step in the discovery of the genetic basis of disease, according to Orchid BioSciences, Inc. (Princeton, NJ, USA), which is offering the service. The company's whole-genome panel provides the most complete genome coverage available commercially today and is more than 99.5% accurate, Orchid states. The whole-genome linkage scan service is flexible, handling individual studies ranging from 50 samples up through thousands of samples. The service uses a SNP panel of 3,200 public domain SNPs evenly spaced across the genome.

"The ability of our whole-genome panel to enable researchers to uncover associations between genotype and phenotype rapidly and cost effectively is an important example of the power and flexibility of our SNP-IT tag array technology,” said Michael Bopyce-Jacino, Ph.D., chief scientific officer and vice president of Orchid.


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