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Immortalized Neural Cell Lines to Aid Drug Discovery

By Biotechdaily staff writers
Posted on 23 May 2002
A library of immortalized human neural cell lines derived from the brain and spinal cord has been launched by CellFactors (Cardiff, UK) for use in a diverse range of pharmaceutical applications.

The company has perfected and patented a novel method of producing stable partially differentiated human cells for therapeutic purposes. Although human and animal tissue culture-based systems have been the mainstay of biomedical research for many years, they do not reflect the physiology of native tissue. CellFactors says it can provide a near infinite supply of stable, replicating research-grade lines.

The company's lead product, Skeletex, is an orthobiologic material that induces the formation of new bone. A parallel development program, dedicated to neural disease therapy and controllable whole cells for implantation, is being developed initially for Parkinson's disease.

"Our expertise in neuroanatomy and molecular cell biology has made this commercial breakthrough possible,” said Dr. George Foster, one of the company's founders.





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