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New Way to Externally View Growing Tumor Cells

By Biotechdaily staff writers
Posted on 22 May 2002
A new external imaging technology provides a view of single tumor cells growing internally in a mouse, greatly increasing detection sensitivity.

Scientists genetically engineered single tumor cells growing in the brain, liver, and pancreas to express the jellyfish green fluorescent protein (GFP), thereby providing an external image of the cells. This was done by inserting a jellyfish gene into the tumor cells. The new technology allows many tumors previously hidden to be clearly seen and enables researchers to visualize and investigate the way cancer spreads, according to the developer, AntiCancer, Inc. (San Diego, CA, USA).

"We can now follow single internal tumor cells externally to develop drugs that prevent recurrence from previously undetectable tumor cells, which is a major cause of death in cancer of the breast and other cancers,” said Shigeo Yagi, vice president and general manager of AntiCancer.




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