Disposable Ultrafiltration Device for Research Scale Separations

Biotech and other life science laboratories will benefit from the launch of a new single-use cross flow ultrafiltration device.

The major international supplier of laboratory equipment and materials Sartorius Stedim Biotech (Goettingen, Germany) has introduced its novel Sartocon Slice 50.


The Sartocon Slice 50 is a single-use cross flow filter device optimized for small-volume process development. It can perform many of the ultrafiltration and diafiltration applications used in downstream processes, such as purification of vaccines, monoclonal antibodies, and recombinant proteins. The system is particularly suitable for use in research laboratories where small scale separations are often required.

The ultrafiltration device is offered as an encapsulated and ready-to-use module with a filter area of 50 square centimeters and is available in a wide variety of molecular weight cutoffs. The self-contained unit eliminates the need for a compression holder, and membranes are available in a choice of two polymers. The Hydrosart membrane is a stable polymer suitable for a broad pH range and can be depyrogenated using NaOH at elevated temperatures. It is extremely hydrophilic, making it non-protein-binding and virtually non-fouling, and delivers an exceptional high flux. The polyethersulfone membrane (PESU), which is well established in the biotechnological and pharmaceutical industries, is a stable polymer that is ideal for a broad pH and temperature range.

Sartocon Slice 50 can easily be interfaced with the Sartorius SARTOFLOW Smart benchtop cross-flow system, as well as with many other laboratory-scale filtration systems.

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