New Line of Sample Preparation Products Facilitates Analysis of Biological Materials

By LabMedica International staff writers
Posted on 31 Aug 2011

A new family of sample preparation products simplifies the extraction of samples from complex biological matrices for chromatographic analysis.

These products – now available from Thermo Fisher Scientific (Milford, MA, USA) - offer a fast and effective method to reduce sample background and concentrate the desired analytes. The “HyperSep SLE” line is available in cartridge and 96-well formats to suit sample size (2 mL to 60 mL) and throughput requirements. The stationary phase consists of specially treated diatomaceous earth and is available in acidified or basified formats to help simplify the protocol when acidic or basic mobile phases are used.

According to Thermo Fisher, HyperSep SLE technology gives greater reproducibility and reliability in sample preparation compared to Liquid/Liquid Extraction (LLE). Unlike protein precipitation techniques, HyperSep SLE removes contaminants such as phospholipids. HyperSep SLE also provides a platform for greater automation and analyte purity, reduces solvent requirements, and can prevent complications such as emulsification of the separate phases.

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Thermo Fisher Scientific