Kit Screens for Neurite Outgrowth Neurotoxin Inducers and Inhibitors

A new assay kit uses high-content screening for imaging and analysis of neurite outgrowth and neuronal cell morphology.

The kit utilizes high-quality, validated, target-specific detection reagents for profiling in a variety of species, including human, mouse, and rat. Large-scale screening is simplified because the assay reagents are stable for 24-hours at room temperature.

The primary antibody is immunofluorescence-based to specifically label neurites and neuronal cell bodies in heterogeneous cell populations. High sensitivity-generating images with high signal-to-background ratios facilitate subsequent high content analysis, making the kit suitable for screening both inducers and inhibitors of neurite outgrowth neurotoxins.

Developed by Millipore corp. (Billerca, MA, USA), the new kit is called the Neurite Outgrowth assay. It is the newest assay kit in Millipore's drug discovery product line.

Millipore's Bioscience Division provides tools, services, and biologic reagents for LifeSciences and supports the discovery and development of new pharmaceuticals. Its product portfolio was enhanced in 2006 by the addition of the Chemicon, Upstate, and Linco product lines.


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