Salmonella Test Uses DNA Hybridization Technology

By Biotechdaily staff writers
Posted on 12 Feb 2007
A Salmonella test combines the specificity of DNA hybridization technology with the ability to rapidly process up to 372 samples simultaneously using a fully automated method, or a small number of samples via a non-automated approach.

In a 15-laboratory collaboration study, the new 24-hour GeneQuence Salmonella test was proven to be an effective test method to rapidly detect the pathogen in food products, such as poultry, eggs, milk chocolate, and dry pet food. In each case, samples were tested using the GeneQuence 24-hour protocol, and either the US Department of Agriculture - Food Safety and Inspection Service (USDA-FSIS) or the US Food and Drug Administration - Bacteriological Analytical Manual (US FDA-BAM) reference method, and results compared.

A major advantage of GeneQuence's DNA hybridization technology is its highly-specific probes, which virtually eliminate false-negatives and greatly minimize the chance of receiving false-positive results due to cross-reactivity with closely-related organisms. This specificity helps eliminate needless confirmation effort, and cost, and helps streamline a company's safety and quality processes. This specificity, coupled with the speed of results, allows companies to ship products sooner with greater confidence, thereby improving their supply chain efficiencies and lowering overall costs.

Neogen Corporation (Lansing, MI, USA) has received Official Method status from the Scientific Association Dedication to Analytical Excellence (AOAC) International for its 24-hour GeneQuence Salmonella diagnostic test system. Each time we receive a validation from an influential third party on any of our tests, it provides further assurance to our many customers that our tests perform as expected. We expect no less, and neither should our customers, said Ed Bradley, Neogen's vice president for Food Safety. The GeneQuence test was shown to produce accurate results in only 24 hours, as opposed to other test systems that can take 48 hours or longer. Compared to other rapid methods, this is the lowest cost per data point of any DNA-based pathogen assay, due to its simplicity. Our customer commitment is clearly reflected in the technologies we offer. We add value to the customer via simple, specific, and scalable diagnostic solutions.




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