Drug Collaboration Based on Natural Products

A drug screening and discovery collaboration has been announced by Hybrigenics SA (Paris, France) and the Shanghai Institute of Materia Medica (SIMM, China), which is affiliated with the Chinese Academy of Sciences.

The companies will seek to identify novel therapeutics in the vast universe of traditional Chinese medicine, using a combination of SIMM's knowledge base of several thousand plant extracts and Hybrigenics' expertise in screening and target validation. Under the terms of the agreement, Hybrigenics will supply targets and a screening assay, while SIMM will provide access to its library of plant extracts based in the Chinese National Center for Drug Screening.

Hybrigenics and SIMM will collaborate on sample screening, hit finding, lead identification and optimization, and related preclinical studies. The partnership will combine Hybrigenics' high-throughput protein interaction mapping with SIMM's expertise in natural product chemistry.

"Hybrigenics' know-how and discovery capabilities should enable us to further explore our natural product library with an aim of developing new drugs in oncology,” said Prof. Jian Ding, deputy director of SIMM.




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