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Informatics Software for Toxicity Prediction

By Biotechdaily staff writers
Posted on 16 Jan 2004
A new informatics system offers a fully integrated software environment for ADME (absorption, distribution, metabolism, excretion) toxicity prediction and includes tools for structure drawing, database management, and customized reporting.

Called KnowItAll, the system allows drug discovery professionals to generate in silico ADME/Tox profiles for potential lead compounds and accelerate lead generation with the largest collection of prediction models, multiple models for more accurate predictions, powerful validation tools to verify models, and integrated tools for improved workflow.

The system was developed by Bio-Rad's Informatics Division (Philadelphia, PA, USA), which specializes in software and database solutions for the pharmaceutical, biotech, and chemical industries. Bio-Rad recently received Frost & Sullivan's ADME/Tox Informatics Product Differentiation Award. Presented annually to one company that demonstrates the ability to produce the most innovative products in this category, the awards are based on market participant interviews, end-user surveys, and extensive secondary research.

"This award distinguishes KnowItAll's ADME/Tox environment from other systems on the market and speaks to the excellence of our ADME/Tox informatics product line as a whole,” said Gregory M. Banik, Ph.D., general manager of Bio-Rad's Informatics Division.



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